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Pathogenesis of postoperative proximal upper limb paralysis following anterior decompression for treating single-level cervical disc herniation |
WANG Hao, GONG Teng |
Department of Orthopaedic Surgery, Characteristic Medical Center of the Chinese People's Armed Police Force, Tianjin 300162,China |
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Abstract Objective To investigate the characteristics and risk factors of secondarily proximal upper limb paralysis (PULP) after anterior decompression of single-segment cervical disc herniation (CDH). Methods The clinical data on 235 patients with single segmental CDH treated with anterior cervical decompression combined with fusion or non-fusion fixation was analyzed retrospectively. The follow-up lasted more than 12 months. There were no significant differences in demographic data between the postoperative PULP group and non-PULP group. According to preoperative clinical manifestations, the patients were divided into two groups: the spinal cord injury group and the nerve root injury group. The decompression segments included C3/ 4, C4/5, C5/6 and C6/7 intervertebral spaces. The postoperative PULP incidence rates were compared between subgroups of different surgical segments or preoperative localized signs. The overall incidence of PULP after upper (lower) intervertebral horizontal decompression with the C5 vertebral body as the boundary was compared. Results All the 26 patients with PULP received non-surgical treatment after operation and achieved basic remission during the last follow-up. In addition to C4/5 intervertebral space and C5 myelomere, PULP could also be secondary to other segmental decompression. There was no significant difference in the incidence of PULP between superior(inferior) two intervertebral spaces with C5 vertebrae as the benchmark or four subaxial intervertebral spaces at the middle and lower level, respectively. The incidence of postoperative PULP among patients concomitant with preoperative myelopathy phenotype was higher than among those with nerve root phenotype, and the difference was of statistical significance. Conclusions Patients who present with predominantly upper motor neuron pathway damage before operation are more vulnerable to PULP after anterior decompression targeted at CDH. The onset of PULP is closely related to the early, reversible and temporary impairment of the system of propriospinal tracts and neurons.
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Received: 20 December 2020
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[1] |
刘晓伟,陈德玉,王新伟,等.颈椎后纵韧带骨化症患者K线对两种颈后路手术疗效的影响[J].中国脊柱脊髓杂志,2013, 23(1):6-10.
|
[2] |
孟 亚,周丽丽,郭永飞,等.颈椎减压术后C5神经根麻痹的研究进展[J].中华骨与关节外科杂志,2016,9(4):342-346.
|
[3] |
马丽红,巩 腾.退变性颈椎疾患减压术后上肢麻痹发生机制研究进展[J].武警医学,2019,30(11):1004-1008.
|
[4] |
Ding H R, Xue Y, Tang Y M, et al. Laminoplasty and laminectomy hybrid decompression for the treatment of cervical spondylotic myelopathy with hypertrophic ligamentum flavum: a retrospective study[J].PloS One, 2014,9(4):95482-959490.
|
[5] |
Hitchon P W, Moritani T, Woodroffe R W,et al. C5 palsy following posterior decompression and instrumentation in cervical stenosis: single center experience and review[J].Clin Neurol Neurosurg,2018,9(174):29-35.
|
[6] |
Chen G D, Wang Y F, Wang Z D, et al. Analysis of C5 palsy in cervical myelopathy with massive anterior compression following laminoplasty[J]. J Orthop Surg Res,2018,13(26):1186-1192.
|
[7] |
Thompson S E, Smith Z A, Hsu W K, et al. C5 palsy after cervical spine surgery: a multicenter retrospective review of 59 cases[J]. Global Spine Journal, 2017,7(15):64S-70S.
|
[8] |
Oh K J, Hong J T, Kang D H, et al. Epidemiology of C5 palsy after cervical spine surgery: a 21-center study[J].Neurospine,2019,16(3):558-562.
|
[9] |
Dombrowski M E,Morales R A,Fourman M S,et al. Prophylactic perioperative dexamethasone decreases the incidence of postoperative C5 palsies after a posterior cervical laminectomy and fusion[J].Spine J, 2018,19(2):253-260.
|
[10] |
Hasegawa K, Homma T, Chiba Y.Upper extremity palsy following cervical decompression surgery results from a transient spinal cord lesion[J].Spine, 2007,32(6):197-202.
|
[11] |
Zhao Y J, Cheng C, Chen H W, et al. Limited laminectomy and foraminal decompression combined with internal fixation for treating multi-segment cervical spondylotic myelopathy:Does it effectively improve neurological function and prevent C5 palsy [J].Medicine,2018,97(47):e13327.
|
[12] |
Takase H, Murata H, Sato M, et al. Delayed C5 Palsy after anterior cervical decompression surgery: preoperative foraminal stenosis and postoperative spinal cord shift increase the risk of palsy[J].World Neurosurg,2018,120(12):e1107-e1119.
|
[13] |
Yang H S, Sun J C, Shi J G, et al. Anterior controllable antedisplacement fusion(ACAF) for severe cervical ossification of the posterior longitudinal ligament: comparison with anterior cervical corpectomy with fusion(ACAF) [J]. World Neurosurgery,2018,4(1):42-53.
|
[14] |
Hirabayashi S, Kitagawa T, Yamamoto Iwao, et al. Postoperative C5 palsy: conjectured causes and effective countermeasures[J]. Spine Surg Relat Res,2019,3(1):12-16.
|
[15] |
Wang T, Wang H, Liu S, et al. Incidence of C5 nerve root palsy after cervical surgery(a meta-analysis and systematic review for last decade) [J]. Medicine,2017,96(45):e8560-e8573.
|
[16] |
Kratzig T, Mohme M, Mende K C, et al. Impact of the surgical strategy on the incidence of C5 nerve root palsy in decompressive cervical surgery[J]. Plos One,2017,12(11):e0188338.
|
[17] |
Hirabayashi S, Kitagawa T, Yamamoto I, et al. Development and achievement of cervical laminoplasty and related studies on cervical myelopathy[J]. Spine Surg Relat Res,2020,4(1):8-17.
|
[18] |
Ando M, Tamaki T, Matsumoto T, et al. Can postoperative deltoid weakness after cervical laminoplasty be prevented by using intraoperative neurophysiological monitoring [J].J Clin Monit Comput,2018,33(1):123-132.
|
[19] |
Krieg S M, Meyer B. C5 palsy after multi-segmental cervical decompression: how can it be avoided [J].Orthopade,2018,47(6):483-488.
|
[20] |
Wang H Y ,Zhang X, Lv B, et al. Analysis of correlative risk factors for C5 palsy after anterior cervical decompression and fusion[J]. Int Clin Exp Med,2015,8(3):3983-3991.
|
[21] |
Oshina M, Segawa,T, Oshima Y, et al. C5 palsy after C5/6/7 posterior foraminal decompression: a case report[J]. Medicine,2020,99(3):e18817-e18820.
|
[22] |
Jack A S, Osburn B R, Tymchak Z A, et al. Foraminal ligament tether upper cervical nerve roots: a potential cause of postoperative C5 palsy[J]. J Brachial Plex Peripher Nerve Inj,2020,15(7):e9-e15.
|
[1] |
. [J]. , 2011, 22(11): 1009-1010. |
|
|
|
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