瑞芬太尼静脉分娩镇痛在妊娠期高血压疾病中的应用

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Abstract Objective To evaluate the efficacy and safety of remifentanil used in labor analgesia among patients with hypertensive disorders of pregnancy (HDP). Methods A total of 80 pregnant women with HDP were selected and randomly divided into two groups (n=40): the observation group (intravenous remifentanil group) and the control group (epidural group). Mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR) and pulse oxygen saturation(SpO₂) were recorded at different time points. VAS scores were measured at each time point, and the levels of satisfaction with labor analgesia were analyzed. The time of each stage of labor, maternal and neonatal adverse reactions were recorded. The Apgar score of newborns was determined and umbilical cord blood gas analysis was performed after delivery. Results There was no significant difference in MAP, HR or RR between the two groups at T₀ (10 min before treatment). However, the MAP of the observation group was significantly higher than that of the control group 10 min (T₁) and 60 min (T₂) after treatment, and 10 min (T₃) and 2 h (T₄) after delivery (P<0.05). As for VAS scores, there was no significant difference between the two groups at T₀ (P>0.05), but they were higher in the observation group than in the control group at each time point (T₁-T₂) after analgesia. There was no significant difference in patients’ level of satisfaction between the two groups (P>0.05). The incidence of hypotension and lower limb numbness in the observation group was lower than in the control group (P<0.05), but the incidence of dizziness was higher (P<0.05). There was no significant difference in blood gas indexes or in the incidence of asphyxia between the two groups (P>0.05). Conclusions Analgesia with remifentanil during labor is stable and ensures good compliance in patients with HDP.

Key words： hypertensive disorders of pregnancy remifentanil labor analgesia patients’ satisfaction

Received: 30 June 2021

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	LI Xiuman
	WANG Weimin
	ZHOU Xian
	LIU Yahua

Cite this article:

LI Xiuman,WANG Weimin,ZHOU Xian等. Applicability of remifentanil in labor analgesia for parturients with HDP[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2021, 32(11): 933-936.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2021/V32/I11/933

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