老年高血压病患者血清pro-BNP及hs-CRP水平与认知功能的相关性

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Abstract Objective To investigate the correlations between levels of pro-natriuretic peptide precursor, hypersensitive C-reactive protein and cognition in elderly patients with hypertension. Methods A total of 178 patients with hypertension who were admitted to our hospital between January 2019 and October 2020 were included in this study. Serum levels of pro-BNP and hs-CRP were detected. The patients were divided into two groups: the cognitive impairment group (n=61) and non-cognitive impairment group (n=117) according to the MMSE score and Montreal Cognitive Assessment score. Results Serum levels of pro-BNP in the cognitive impairment group were significantly higher than those of the non-cognitive impairment group(426.52±18.72 pg/ml vs 120.36±15.61 pg/ml, P=0.000), so were the levels of hs-CRP in the cognitive impairment group(5.91±0.46 ng/L vs 3.27±0.52 ng/L,P=0.000). Conclusions Serum levels of pro-BNP and hs-CRP are closely related to the occurrence of cognitive dysfunction. It is suggested that these levels be monitored in the elderly patients with hypertension so as to prevent cognitive dysfunction.

Key words： hypertension pro-brain natriuretic peptide high-sensitivity C-reactive protein cognitive function

Received: 30 August 2021

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	QUAN Qingyun
	ZHAO Xiaojuan
	ZHANG Yu
	WANG Jianguo
	LI Qian

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QUAN Qingyun,ZHAO Xiaojuan,ZHANG Yu等. Correlations between serum pro-BNP and hs-CRP levels and cognition in elderly patients with hypertension[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(1): 57-59.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2022/V33/I1/57

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