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Effect of early mobilities on safety in ICU patients with continuous renal replacement therapy |
ZHAO Hongyu1, TANG Sheng2, MA Yanlan3, LUO Sha4, LI Lina5, CAO Yurui1, YANG Ning1 |
1. Medical School of Chinese PLA,Beijing 100853,China; 2. Department of SICU,4. Department of KICU, 5. Department of RICU, the First Medical Centre of Chinese PLA General Hospital,Beijing 100853; 3. Department of Medical Training Center,Chinese PLA General Hospital,Beijing 100853,China |
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Abstract Objective To investigate the effect of early mobilities on the safety in ICU patients with continuous renal replacement therapy (CRRT). Methods Eighteen patients with CRRT were randomly divided into experimental group (n=9) and control group (n=9) by computer random number table method. The control group was given routine treatment and nursing, while the experimental group performed active and passive range of motion during CRRT on-machine.The CRRT pressure parameters (arterial pressure PA, venous pressure PV, prefiltration pressure PBE, and Transmembrane pressure TMP) and vital signs (blood pressure BP, heart rate HR, respiratory rate RR, blood oxygen saturation SpO2) were compared before (0 min), during (15 min) and after (30 min) the mobility, and the occurrence of adverse events in the two groups were also compared. Results All the patients completed the study, and the experimental group completed 41 times of early mobilities, while the control group were recorded 36 times. There was no significant difference in CRRT pressure parameters between the two groups at different time points (0, 15, 30 min) (P>0.05). There was statistically significant difference in PA at 30 min[(-80.41±31.91)mmHg] and at 0 min[(-76.54±33.59)mmHg] in the experimental group (P=0.005); PV at 15 min [(57.05±20.99)mmHg] and at 0 min[(54.80±22.82)mmHg], the difference was statistically significant (P=0.024); the PV at 30 min [(59.85±21.73)mmHg] was significantly different from that at 0 min (P=0.000). There was statistically significant difference between TMP at 30 min[(84.39±25.80)mmHg] and TMP at 0 min[(80.78±27.69)mmHg] (P=0.036). There was no significant difference in vital signs between the two groups at different time points (0, 15, 30 min), and there was no significant difference between different time points and 0 min. There was no significant difference in adverse events between the two groups. Conclusion It is safe to carry out early mobilities in ICU patients with c CRRT.
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Received: 28 January 2022
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[1] |
李 果.武汉市连续性肾替代治疗应用现况及成本测算研究[D].武汉:武汉大学,2018.
|
[2] |
Latronico N, Bolton C F. Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis [J]. Lancet Neuro, 2011, 10(10): 931-941.
|
[3] |
Raurell T M,Arias R S,Martí J D,et al.Care and treatments related to intensive care unit-acquired muscle weakness:a cohort study[J].Aust Crit Care,2021,34(5):435-445.
|
[4] |
Aerde N, Meersseman P, Debaveye Y, et al. Five-year impact of ICU-acquired neuromuscular complications: a prospective, observational study [J]. Intensive Care Med, 2020, 46(6):1184-1193.
|
[5] |
Hermans G,Mechelen H,Clerckx B,et al.Acute outcomes and 1-year mortality of intensive care unit-acquired weakness.a cohort study and propensity-matched analysis[J].Am J Respir Crit Care Med,2014,190(4):410-420.
|
[6] |
Meyer F C H, Malewicz N M, Rath S, et al. Incidence, time course and influence on quality of life of intensive care unit-acquired weakness symptoms in long-term intensive care survivors [J]. J Intensive Care Med, 2021, 36(11): 1313-1322.
|
[7] |
Fan E,Dowdy D W,Colantuoni E,et al.Physical complications in acute lung injury survivors:a two-year longitudinal prospective study[J].Crit Care Med,2014,42(4):849-859.
|
[8] |
Potter K, Miller S, Newman S. Environmental factors affecting early mobilization and physical disability post-intensive care: an integrative review through the lens of the world health organization international classification of functioning, disability, and health [J]. Dimens Crit Care Nurs : DCCN, 2021, 40(2): 92-117.
|
[9] |
Mayer K P,Joseph I E,Robinson L E,et al.Safety and feasibility of physical rehabilitation and active mobilization in patients requiring continuous renal replacement therapy:a systematic review[J].Crit Care Med,2020,48(11):e1112-e1120.
|
[10] |
陈丽花,曾丽婷,徐蒙蒙,等.ICU连续性肾脏替代治疗病人早期运动的安全性与可行性研究[J].护理研究,2020,34(3):497-499.
|
[11] |
黄卓凡,谢 静,陈奕冰,等.ICU连续性肾脏替代治疗期间早期活动可行性研究[J].齐齐哈尔医学院学报,2020,41(15):1962-1964.
|
[12] |
冯 哲. 全国多中心住院患者急性肾损伤前瞻性流行病学研究[D].北京:解放军医学院,2015.
|
[13] |
血液净化急诊临床应用专家共识组. 血液净化急诊临床应用专家共识[J]. 中华急诊医学杂志,2017,26(1):24-36.
|
[14] |
Lee H,Ko Y J,Jung J,et al.Monitoring of potential safety events and vital signs during active mobilization of patients undergoing continuous renal replacement therapy in a medical intensive care unit[J].Blood Purif,2016,42(1):83-90.
|
[15] |
Brownback C A,Fletcher P,Pierce L N,et al.Early mobility activities during continuous renal replacement therapy[J].Am J Crit Care,2014,23(4):348-351.
|
[16] |
Marusic U, Narici M, Simunic B, et al. Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review [J]. J Appl Physiol, 2021, 131(1): 194-206.
|
[17] |
Dirks M L, Wall B T, Valk B, et al. One week of bed rest leads to substantial muscle atrophy and induces whole-body insulin resistance in the absence of skeletal muscle lipid accumulation [J]. Diabetes, 2016, 65(10): 2862-2875.
|
[18] |
Brower R G. Consequences of bed rest [J]. Crit Care Med, 2009, 37(10 Suppl): S422-428.
|
[19] |
Yu M D, Zhang H Z, Zhang Y, et al. Relationship between chronic kidney disease and sarcopenia [J]. Sci Rep, 2021, 11(1): 20523.
|
[20] |
Wang Y T,Haines T P,Ritchie P,et al.Early mobilization on continuous renal replacement therapy is safe and may improve filter life[J].Crit Care,2014,18(4):R161.
|
[21] |
Toonstra A L,Zanni J M,Sperati C J,et al.Feasibility and safety of physical therapy during continuous renal replacement therapy in the intensive care unit[J].Ann Am Thorac Soc,2016,13(5):699-704.
|
[22] |
王渝强,郭应强,黄 维,等.留置股血管导管的危重症患者早期活动安全性与可行性的定性系统评价[J/OL].中国胸心血管外科临床杂志: 1-7[2022-02-12].http://kns.cnki.net/kcms/detail/51.1492.R.20211228.1209.020.html.
|
[23] |
Lima N P,Silva G M,Park M,et al.Mobility therapy and central or peripheral catheter-related adverse events in an ICU in Brazil[J].J Bras Pneumol,2015,41(3):225-230.
|
[24] |
易晓平,郭 红, 申艳玲,等.成年人ICU早期活动护理实施阻碍因素的系统评价与汇总分析[J].中国实用护理杂志,2021,37(34):2708-2714.
|
[1] |
. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(2): 159-161. |
|
|
|
|