肾小球滤过率、肌钙蛋白T水平与肾性贫血的相关性分析

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Abstract Objective To explore the relationship between cardiac troponin T (cTnT),glomerular filtration rate (GFR),and renal anemia (RA) respectively by analyzing levels of three indexes among hemoglobin (Hgb), GFR and cTnT in non-dialysis patients with chronic kidney disease (CKD). Methods The levels of Hgb, cTnT and GFR of 891 inpatients with non-dialysis CKD in our hospital were analyzed. According to Hgb level, patients were divided into four anemia groups of no, mild, moderate and severe, and levels of GFR and cTnT were observed respectively in each group. According to GFR level,patients were divided into CKD1-5 stages,and the Hgb level at each stage of CKD and the proportion of Hgb level below 90g/L were observed and analyzed. Results In non-dialysis patients, the GFR (ml/min) levels were 62.6(46.3,82.6), 37.9(25.5,51.4), 20.7(14.7,29.9), 16.4(13.0,27.4) in no, mild, moderate and severe anemia group, respectively. The GFR levels of different anemia groups showed significant differences with statistical significance(P<0.05). The GFR levels decreased gradually with the aggravation of anemia. Pearson-test showed a positive linear relationship between GFR and Hgb (R=0.653, P<0.05).The levels of cTnT (ng/ml) were 0.010(0.006,0.015), 0.016(0.011,0.028),0.028 (0.016,0.045), 0.036(0.021,0.046) in no, mild, moderate and severe groups, respectively. CTnT level increased gradually with the aggravation of anemia. Pearson-test showed a negative linear relationship between cTnT and Hgb (R=-0.300, P< 0.05).With increased CKD staging, the average level of Hgb gradually decreased, and the proportion of Hgb below 90 g/L gradually increased. Conclusions Actively ameliorating anemia in non-dialysis patients with CKD can delay renal function progression and improve myocardial status.

Key words： renal anemia cardiac troponin T hemoglobin glomerular filtration rate kidney disease

Received: 01 December 2021

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	Articles by authors
	PAN Dezhang
	LONG Zhijun
	NIE Shanhua
	PANG Yutao
	XIAO Ruifeng

Cite this article:

PAN Dezhang,LONG Zhijun,NIE Shanhua等. Relationship between glomerular filtration rate, cardiac troponin T and renal anemia[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(5): 404-407.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2022/V33/I5/404

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