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Influencing factors of in-hospital mortality of aged patients |
ZHANG Jing, XUE Hengyi, LI Yanyan, CAO Yukun, FANG Zhou, ZHANG Haitao |
Department of Cardiology, Characteristic Medical Center of PLA Air Force, Beijing 100142 China |
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Abstract Objective To analyze the characteristics of nonagenarian in hospital and investigate the influencing factors associated with the in-hospital mortality. Methods Two hundred and twenty-eight nonagenarian patients admitted in our department from January 2015 to December 2021 were collected. According to their in-hospital outcome the patients were divided into death group (n=48) and survival group (n=180). The general information, results of biochemical indices at admission and Barthel index (BI) were compared between the two groups , and the influencing factors associated with in-hospital mortality were analyzed. Results Compare with the patients in the survival group, those from the death group had higher rations of anemia, hypoalbuminemia, heart failure, infectious disease and cancer, lower BI [(32.56±23.74) vs (69.72±15.94)], decreased levels of hemoglobin [(103.21±18.86) vs (119.34±12.56)], eGFR[(56.32±21.34) vs (60.53±14.54)] and albumin [(35.23±3.65) vs (39.32±4.32)], but larger white blood cell count [(8.98±2.45) vs (6.56±2.23)] and BNP [(450.51±90.42) vs (356.65±70.33)]. The difference had statistically significant. Logistic regression analysis indicated that severe disability (OR=5.09, 95%CI 2.02-12.76, P=0.001), anemia (OR=6.08, 95%CI 3.18-13.03, P=0.001), infection (OR=1.24, 95% CI 1.05-2.10, P=0.012), hypoalbuminemia (OR=5.43, 95%CI 2.54-11.83, P=0.002) were risk factors of in-hospital death. Conclusions The inpatients aged 90 or above should actively improve their ability of daily living after admission, the malnutrition and anemia should be monitored, reducing the rate of infection, which is of positive significance in reducing the mortality in the elderly.
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Received: 26 May 2022
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