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Clinical study and safety analysis of laparoscopic assisted stage I resection and anastomosis in treatment of left colon cancer complicated with acute ileus after intestinal decompression |
DA Buxilite, ZHENG Hao, HAN Chengxin |
Department of General Surgery, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China |
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Abstract Objective To analyze the clinical efficacy and safety of laparoscopic assisted stage I resection and anastomosis in the treatment of left colon cancer complicated with acute ileus. Methods A total of 66 patients with left colon cancer complicated with acute ileus who were admitted to our hospital from June 2015 to November 2021 were selected as the research objects. The control group (33 cases) were treated with stage I resection and anastomosis, and the research group (33 cases) were treated with stage I laparoscopic-assisted resection and anastomosis after decompression. The clinical efficacy of the two groups was analyzed. The indexes related to operation and postoperative effect of the patients were compared, inflammatory factors indexes of patients were detected, complications of patients were recorded, and the quality of life of patients was evaluated. Results After operation, the total effective rate of the study group (100.00%) was significantly higher than that of the control group (84.85%) (P<0.05). The number of lymph node clearance in the study group(12.34±1.34) was significantly higher than that in the control group (11.21±1.08), and the recovery time of gastrointestinal function[(3.40±0.66)d], ambulation time[(41.53±4.30) h]and hospitalization time[ (18.31±3.69) d]were significantly lower than those in the control group (P<0.05). The levels of serum C-reactive protein (CRP)[ (30.95±4.00) mg/L]and tumor necrosis factor-α (TNF-α)[ (19.18±1.90)pg/ml]in the study group were significantly lower than those in the control group one week after operation (P<0.05). The total incidence of complications in the study group (9.09%) was significantly lower than that in the control group (30.30%) (P<0.05). The scores of physical function, psychological function, material life and social function in the study group were significantly higher than those in the control group (P< 0.05). Conclusions Laparoscopic stage I resection and anastomosis after intestinal decompression can effectively improve the clinical efficacy of patients with left colon cancer complicated with acute ileus, and can promote gastrointestinal function recovery, shorten the length of hospital stay, and improve the quality of life, with high safety, which is worthy of clinical application.
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Received: 30 August 2022
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[1] |
Ma W, Zhang Q, Li X, et al. IPM712, a vanillin derivative as potential antitumor agents, displays better antitumor activity in colorectal cancers cell lines[J]. Eur J Pharm Sci, 2020,152: 105464.
|
[2] |
朱跃坤, 朴大勋. 左半结肠癌致肠梗阻治疗中的临床特点[J]. 临床外科杂志, 2021,29(5):418-420.
|
[3] |
杜峻峰, 李世拥, 陈 纲,等. 基于膜解剖的腹腔镜脾曲结肠癌根治术33例临床分析[J]. 中华普外科手术学杂志, 2020, 14(3):256-259.
|
[4] |
侯建峰, 王卫刚.Ⅰ期切除吻合术治疗左半结肠癌合并急性肠梗阻的可行性研究[J]. 实用临床医药杂志, 2019,23(12):36-38.
|
[5] |
何建智. 腹腔镜与开腹手术治疗结肠癌的疗效比较及对机体免疫功能的影响[J]. 中国肛肠病杂志, 2022,42(4):14-16.
|
[6] |
何锦生, 蔡伟勤, 姚玉玲.Ⅰ期切除吻合术在左半结肠癌合并急性肠梗阻患者中的应用[J].海南医学, 2020,31(15):1972-1974.
|
[7] |
马 磊,曹 军,王 欣,等. 腹腔镜治疗结肠癌合并肠梗阻的临床效果及预后影响因素分析[J]. 中国现代普通外科进展, 2022,25(2):143-147.
|
[8] |
Wang Y Y, Zhou Q. The effect of accelerated rehabilitation nursing on postoperative recovery, nutritional status, and psychological status in patients with gastric cancer[J]. Am J Transl Res, 2021,13(4):3666-3673.
|
[9] |
Xiao S J, Zhao C Z, Sun J,et al. Effect of high-quality nursing on negative psychological moods and quality of life of elderly patients with hypertension[J]. Am J Transl Res, 2021,13(4):3710-3716.
|
[10] |
韩加刚, 王振军. 梗阻性左半结肠癌治疗新策略-支架扩张联合新辅助化疗[J]. 临床外科杂志, 2020,28(5):401-403.
|
[11] |
王 刚, 毕 聪, 潘 鑫. DSA引导下自膨式金属支架治疗晚期左半结肠癌合并急性肠梗阻的临床分析[J]. 现代肿瘤医学, 2020,28(12):2075-2079.
|
[12] |
程思俊, 杨驭媒, 袁 波,等. 可扩张支架置入联合新辅助化疗后行择期左半结肠根治术治疗梗阻性左半结肠癌[J]. 中华普外科手术学杂志:电子版, 2021,5(4):430-433.
|
[13] |
傅厚丰,李 炳,梁振雄,等. 肠减压后腹腔镜下尾侧中间联合入路方法治疗右半结肠癌的效果分析[J]. 临床和实验医学杂志, 2022,21(3):307-310.
|
[14] |
程康文, 王贵和, 束宽山, 等. 两种机械吻合方式在腹腔镜辅助右半结肠癌术中的回顾性对照研究[J]. 中国普外基础与临床杂志, 2019,26(7):856-860.
|
[15] |
陈志男, 侯利民, 马 静. 左半结肠癌及直肠癌并肠梗阻手术中肠道灌洗套件的应用[J]. 中国临床研究, 2021,34(5):638-641.
|
[16] |
李 吉, 闫峥峥, 何若冲. 一期病灶切除肠吻合术在梗阻性左半结肠癌治疗中的应用研究进展[J]. 山东医药, 2021,61(15):89-93.
|
[17] |
仝 聪, 宗 伟, 李家扬,等. 肠道支架置入联合腹腔镜手术治疗左半结肠癌梗阻的疗效分析[J]. 现代肿瘤医学, 2022,30(3):487-491.
|
[18] |
巫 诚, 俞金龙, 邹兆伟. 肠减压后腹腔镜辅助右半结肠切除术在右半结肠癌伴肠梗阻中的应用[J]. 重庆医学, 2021,50(23):3970-3973,3977.
|
[19] |
中国研究型医院学会机器人与腹腔镜外科专业委员会, 中国医师协会内镜医师分会腹腔镜外科专业委员会, 中华医学会外科学分会腹腔镜与内镜外科学组. 胃癌4K腹腔镜手术操作标准专家共识(2020版)[J]. 中华消化外科杂志, 2020,19(Z1):1-10.
|
[20] |
郭跃虎, 牛志燕, 王 波,等. 经肛门肠梗阻导管减压与经肠道支架植入术减压后腹腔镜手术治疗梗阻性结直肠癌的效果分析[J]. 中国药物与临床, 2020,20(7):1126-1127.
|
[1] |
. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(8): 713-714. |
|
|
|
|