富血小板纤维蛋白治疗糖耐量受损患者牙周垂直型骨吸收的效果评价

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Abstract Objective To investigate the effects of platelet-rich fibrin (PRF) on periodontal vertical alveolar bone resorption in patients with impaired glucose tolerance.Methods Sixty patients with chronic periodontitis with abnormal glucose tolerance were selected and randomly divided into control (n=30) and PRF (n=30) groups. On the day of periodontal surgery and 6 months after surgery, the serum levels of inflammatory factor interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α), bleeding index (BI), probing depth (PD), attachment loss (AL), bone mean density (BMD) and the height of alveolar in defect zone were determined.Results Six months after periodontal surgery, compared with the control group, IL-6 and TNF-α levels in serum, PD and AL all decreased in the PRF group (P＜0.05).Conclusions PRF intervention can reduce inflammatory factor levels in serum and promote periodontal soft tissue regeneration.

Key words： platelet-rich fibrin impaired glucose tolerance chronic periodontitis inflammatory factors

Received: 17 October 2022

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	Articles by authors
	ZHANG Chenxi
	TIAN Xiaoyu
	DANG Ruijie
	ZHAO Lisheng

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ZHANG Chenxi,TIAN Xiaoyu,DANG Ruijie等. Effects of platelet-rich fibrin on periodontal vertical alveolar bone resorption in patients with impaired glucose tolerance[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2023, 34(8): 678-681.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2023/V34/I8/678

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