后腹腔镜下肾部分切除术和根治性肾切除术治疗肾肿瘤的效果比较

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1296 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To compare perioperative indexes, renal function indexes and prognosis of patients with renal tumor after retrolaparoscopic partial nephrectomy and radical nephrectomy. Methods A total of 118 patients with stage cT₁-T₂ renal tumor admitted to Characteristics Medical Center of Chinese People’s Armed Police Force from January 2019 to April 2022 were selected to undergo radical laparoscopic nephrectomy (62 cases in the control group) and partial nephrectomy (56 cases in the observation group) according to their wishes. The indexes of operation, inflammatory factors, cellular immunity, renal function, postoperative complications and prognosis were compared between the two groups. Results The observation group had smaller tumor diameter, lower R.E.N.A.L. score and longer operation time, and the differences were statistically significant compared with the control group (P<0.05).There was no statistically significant difference in inflammatory cytokines or cellular immune indexes between the two groups before and 24 h after surgery (P>0.05).After surgery, the levels of BUN and SCR decreased and eGFR increased in the observation group, with statistically significant differences compared with the control group (P<0.05).At the last follow-up, the percentage of eGFR decrease in the observation group (10.24%) was lower than that in the control group (33.81%).The incidence of cardiovascular events and deaths in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusions Compared with retrolaparoscopic radical nephrectomy, retrolaparoscopic partial nephrectomy does not increase perioperative risk in patients with renal tumor and improve prognosis by preserving more renal function.

Key words： retrolaparoscopic radical nephrectomy retrolaparoscopic partial nephrectomy renal tumor perioperative renal function

Received: 21 June 2023

ZTFLH:

R737.11

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	SU Wei
	ZHU Mingyang

Cite this article:

SU Wei,ZHU Mingyang. Comparison of efficacy of retrolaparoscopic partial nephrectomy and radical nephrectomy in treatment of renal tumors[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2023, 34(11): 921-925.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2023/V34/I11/921

[1]	Mier J W. The tumor microenvironment in renal cell cancer[J].Curr Opin Oncol, 2019, 31(3): 194-199.
[2]	Yang B, Ma L L, Qiu M, et al. A novel nephrometry scoring system for predicting peri-operative outcomes of retroperitoneal laparoscopic partial nephrectomy[J]. Chin Med J (Engl), 2020, 133(5): 577-582.
[3]	Zhang Y,Yang J,Zhang M,et al.Thyroid follicular carcinoma like renal tumor: a case report and literature review[J]. Medicine (Baltimore), 2018, 97(21): e10815.
[4]	Yuan B, Wang Y, Gao J, et al.Lower pole approach in retroperitoneal laparoscopic radical nephrectomy: a new approach for the management of renal vascular pedicle[J]. World J Surg Oncol, 2018, 16(1): 31.
[5]	Tanaka R,Tomiyama E,Sekii Y,et al.Disturbance of consciousness in a patient with an indwelling lumbar-peritoneal shunt following retroperitoneal laparoscopic radical right nephrectomy: a case report[J]. Hinyokika Kiyo, 2019, 65(7): 287-289.
[6]	高锡强.根治性肾切除术与保留肾单位的肾部分切除术治疗肾癌的临床疗效对比[J].当代医学, 2019, 25(3): 112-114.
[7]	杨前进,周晓晓,侯莉莉,等.后腹腔镜保留肾单位术和根治性肾切除术治疗局限性T1b、T2a期肾癌效果分析[J].河南外科学杂志, 2019, 25(3): 60-62.
[8]	Huang Y S,Chin W C, Guilleminault C,et al. Inflammatory factors: nonobese pediatric obstructive sleep apnea and adenotonsillectomy[J]. J Clin Med, 2020, 9(4): 1028.
[9]	Qin F,Lv Q,Hong W,et al.Association between CD4/CD8 ratio recovery and chronic kidney disease among human immunodeficiency virus-Infected patients receiving antiretroviral therapy: a 17-year observational cohort study[J]. Front Microbiol, 2022, 13: 827689.
[10]	Zhang N,Liu J,Qiu Z,et al.Shenfu injection for improving cellular immunity and clinical outcome in patients with sepsis or septic shock[J]. Am J Emerg Med, 2017, 35(1): 1-6.
[11]	栗恒,李宏彬,夏钢,等.传统开放性肾癌根治性切除术与后腹腔镜肾癌根治性切除术对肾癌患者的临床疗效及对肾功能的影响[J].癌症进展, 2019, 17(14): 1679-1682.
[12]	Danilovic A,Ferreira T A C,Maia G V A,et al.Predictors of surgical complications of nephrectomy for urolithiasis[J].Int Braz J Urol, 2019, 45(1): 100-107.
[13]	董毅,王正,王辉,等.肾部分切除术与根治性肾切除术治疗老年cT1～2期肾肿瘤围手术期指标及肾功能随访分析[J].中华泌尿外科杂志, 2019, 40(5): 351-355.
[14]	Smith M, Herrington W G, Weldegiorgis M,et al.Change in albuminuria and risk of renal and cardiovascular outcomes: natural variation should be taken into account[J]. Kidney Int Rep, 2018, 3(4): 939-949.
[15]	Kim B S,Kim T H,Oh J H,et al.Association between preoperative high sensitive troponin Ⅰ levels and cardiovascular events after hip fracture surgery in the elderly[J]. J Geriatr Cardiol,2018,15(3):215-221.