飞行人员升主动脉扩张发病情况及其影响因素分析

Abstract
Figure/Table
References
Related Citation (1)

Download: PDF (1009 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the incidence and influencing factors of ascending aorta dilatation among pilots. Methods Clinical data of 223 military pilots hospitalized in Characteristics Medical Center of PLA Air Force from January 2018 to December 2022 were collected, and the incidence and its influencing factors of ascending aorta dilatation were analyzed. Results The prevalence rate of ascending aorta dilatation was 6.73%, which was statistically significant with flight time and age. The prevalence rate increased with flight time and age. The prevalence rate of flight time above 5000 hours was 17. 02%, and that above 45 years old was 15.09%. It was also statistically significant with blood pressure, blood lipids and smoking. The prevalence of ascending aorta dilatation in pilots with elevated blood pressure, dyslipidemia and smoking was higher. There was no statistically significant difference between pilots with different aircraft types. Conclusions Ascending aortic dilatation is relatively common among military pilots. Flight time, age, blood pressure, blood lipids and smoking are influencing factors of ascending aorta dilatation.

Key words： ascending aortic dilatation aeromedicine pilot

Received: 10 July 2023

ZTFLH:

R856.5

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CAO Yukun
	YANG Ting
	FANG Zhou
	XUE Hengyi
	LI Yanyan
	REN Xinghua
	ZHANG Haitao
	ZHANG Jing

Cite this article:

CAO Yukun,YANG Ting,FANG Zhou等. Analysis of incidence and influencing factors of ascending aorta dilatation among pilots[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2023, 34(12): 1017-1020.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2023/V34/I12/1017

[1]	Erbel R, Aboyans V, Boileau C,et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The task force for the diagnosis and treatment of aortic diseases of the European society of cardiology (ESC)[J].Eur Heart J, 2014, 35(41): 2873-2926.
[2]	Geronzi L, Haigron P, Martinez A,et al. Assessment of shape-based features ability to predict the ascending aortic aneurysm growth[J].Front Physiol, 2023, 14: 1125931.
[3]	潘胜梅, 张越, 孙振芳. 民航首次申请延飞飞行员升主动脉扩张发病情况与影响因素调查[J]. 中华航空航天医学杂志,2013,24(3):221-223.
[4]	王翔, 王志斌, 孙品, 等. 超声测量心外膜脂肪厚度与升主动脉扩张的相关性研究[J]. 医学影像学杂志,2015,25(3):437-439.
[5]	王增武, 刘静, 李建军, 等. 中国血脂管理指南(2023年)[J]. 中国循环杂志,2023,38(3):237-271.
[6]	郑军, 肖晓光, 姚克纯, 等. 不同水平+G_z暴露后飞行员心脏功能的变化[J]. 中华航空航天医学杂志,2004(2):4-8.
[7]	张俊, 肖平喜, 刘佳怿, 等. 国人胸主动脉扩张的最佳阈值及其影响因素分析[J]. 临床放射学杂志,2020,39(11):2212-2216.
[8]	Churchill T W, Groezinger E, Kim J H, et al. Association of ascending aortic dilatation and long-term endurance exercise among older masters-level athletes[J]. JAMA Cardiol, 2020, 5(5): 522-531.
[9]	马玉梅. 高血压与升主动脉扩张的二维超声心动图相关性分析[J]. 中西医结合心血管病电子杂志, 2021, 9(27): 127-128,199.
[10]	王翔, 侯志辉, 安云强, 等. 采用冠状动脉CTA探究血压对主动脉根部及升主动脉的影响[J]. 国际医学放射学杂志,2019,42(3):274-278.
[11]	DePaolo J, Levin M G, Tcheandjieu C, et al. Relationship between ascending thoracic aortic diameter and blood pressure: a mendelian randomization study[J]. Arterioscler Thromb Vasc Biol, 2023, 43(2): 359-366.
[12]	Zhao Q, Zmuda J M, Kuipers A L, et al. Muscle attenuation is associated with newly developed hypertension in men of african ancestry[J]. Hypertension, 2017, 69(5): 957-963.
[13]	Stoiber L, Mahfoud F, Zamani S M, et al. Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial[J]. Clin Res Cardiol, 2018, 107(8): 642-652.
[14]	Ito S, Lu H S, Daugherty A, et al.Embryonic heterogeneity of smooth muscle cells in the complex mechanisms of thoracic aortic aneurysms[J].Genes (Basel), 2022, 13(9):1618.
[15]	Barkas F, Nomikos T, Liberopoulos E, et al.Diet and cardiovascular disease risk among individuals with familial hypercholesterolemia: systematic review and meta-analysis[J].Nutrients, 2020, 12(8):2436.
[16]	Thompson G R. Atherosclerosis in cholesterol-fed rabbits and in homozygous and heterozygous LDL receptor-deficient humans[J]. Atherosclerosis, 2018, 276: 148-154.
[17]	Paul T K, Alamin A E, Subedi P, et al. Association between cardiovascular risk factors and the diameter of the thoracic aorta in an asymptomatic population in the central appalachian region[J]. Am J Med Sci, 2021, 361(2): 202-207.
[18]	Sakalihasan N, Michel J B, Katsargyris A,et al. Abdominal aortic aneurysms[J].Nat Rev Dis Primers, 2018, 4(1): 34.
[19]	Varela-Carver A, Parker H, Kleinert C, et al. Adverse effects of cigarette smoke and induction of oxidative stress in cardiomyocytes and vascular endothelium[J]. Curr Pharm Des, 2010, 16(23): 2551-2558.
[20]	Sevilla-Montero J, Labrousse-Arias D, Fernández-Pérez C, et al. Cigarette smoke directly promotes pulmonary arterial remodeling and Kv7.4 channel dysfunction[J]. Am J Respir Crit Care Med, 2021, 203(10): 1290-1305.