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Correlation analysis between smoking and glomerular hyperfiltration in male recruits |
ZHANG Chun1, AN Lianqing2, CHEN Junhua3, LIU Zhenjiang4, WANG Lixiang5, LI Haiyang5, CAI Guangyan6 |
1. Department of Nephrology;2. Emergency Department;3. Department of Cardiology;4. Department of Pharmacy, Xinjiang Autonomous Regional Corps Hospital of Chinese People's Armed Police Force, Urumqi 830091, China; 5. Health team of Altai detachment of Xinjiang Autonomous Regional Corps Hospital of Chinese People's Armed Police Force, Altai 836500, China; 6. Department of Nephrology, the First Medical Centre of PLA General Hospital, Beijing 100853, China |
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Abstract Objective To analyze the correlation between smoking and glomerular hyperfiltration in male recruits. Methods A cross-sectional study was conducted on 1898 male recruits in a military unit in 2023, who were classified according to different smoking status and different estimated glomerular filtration rate, and the influence on estimated glomerular filtration rate was evaluated by binary logistic regression analysis. Results Univariate analysis showed that the estimated glomerular filtration rate was statistically significant with smoking, smoking index, body mass index, systolic blood pressure, diastolic blood pressure, heart rate, red blood cell count, and serum creatinine (P<0.05). Multivariate logistic regression analysis showed that smoking was independently associated with glomerular hyperfiltration compared with non-smokers (OR=2.029, 95%CI: 1.104-3.731), the probability of glomerular hyperfiltration was more than 2 times. Compared with mild smoking index, heavy smoking index was associated with glomerular hyperfiltration (OR=2.497, 95%CI: 1.010-6.175). Conclusions Smoking is an influencing factor in estimating glomerular filtration rate in male recruits and is independently associated with glomerular hyperfiltration.
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Received: 18 February 2024
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