冠心病伴慢性心力衰竭患者心率变异性及其与病情严重程度的相关性

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Abstract Objective To explore the characteristics of heart rate variability in patients with coronary heart disease (CHD) accompanied by chronic heart failure (CHF) and analyze its correlation with the severity of the disease. Methods The clinical data of 84 patients with coronary heart disease in Traditional Chinese Medicine Hospital of Changsha from January 2022 to May 2024 were retrospectively analyzed and divided into two groups based on whether they had CHF or not, including 42 patients with CHD alone (CHD group) and 42 patients with CHD accompanied by CHF (CHD accompanied by CHF group), while 42 healthy subjects admitted to the same hospital during the same period were used as control group, and 24-hour holter electrocardiogram was used to observe heart rate variability indicators and its correlation with the severity of the disease. Results The standard deviation of R-R intervals (SDNN), root mean square of adjacent sinus R-R interval difference (rMMD), percentage of sinus rhythm with adjacent sinus R-R interval difference ≥ 50 ms (PNN50), ratio of total sinus R-R intervals to the height of sinus R-R interval histogram (TRI), and fastest heart rate in the CHD accompanied by CHF group were lower than those in the control group. In addition, the SDNN, root mean square of adjacent sinus R-R interval difference (rMMD), PNN50, and TRI in the CHD accompanied by CHF group were higher than those in the CHD group (P<0.05). According to New York Heart Association (NYHA) grading system, patients with CHD accompanied by CHF were mostly diagnosed with mild heart function impairment, accounting for 40.48%, followed by moderate to severe heart function impairment. SDNN, rMSSD, PNN50, and TRI of grade IV patients were lower than those of grade Ⅱ and Ⅲ, and all indicators of grade Ⅲ patients were lower than those of grade Ⅱ (P<0.05). Pearson correlation analysis showed a negative correlation (P<0.05) between NYHA grade and heart rate variability indicators. Conclusions Patients with CHD or with CHD accompanied by CHF exhibit cardiac autonomic dysfunction and decreased heart rate variability, accompanied by different degrees of cardiac function impairment, and the indicators of heart rate variability is negatively correlated with NYHA.

Key words： coronary heart disease chronic heart failure characteristics of heart rate variability heart function degree of illness correlation

Received: 07 November 2024

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	LIANG Rong

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LIANG Rong. Characteristics of heart rate variability in patients with coronary heart disease accompanied by CHF and its correlation with the severity of the disease[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(2): 138-140.

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https://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR https://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2025/V36/I2/138

[1]	Zhang Y, Wang J, Xu Y. Value of heart rate variability on dynamic electrocardiogram in predicting ventricular fibrillation in elderly acute myocardial infarction patients[J]. Ann Palliat Med,2020,9(5):3488-3494.
[2]	王海郦,陈莉.帕金森病伴慢性心力衰竭患者心率变异性与心功能和预后的关系[J].中国医师杂志,2020,22(9):1307-1310.
[3]	徐晨曦,鹿小燕,于龄华,等.心率变异性与冠心病血瘀证、冠状动脉狭窄程度的相关性[J].中日友好医院学报,2023,37(2):90-92,96.
[4]	颜红兵,马长生,霍勇. 临床冠心病诊断与治疗指南[M]. 北京:人民卫生版社,2010:104-106.
[5]	中华医学会心血管病学分会心力衰竭学组,中国医师协会心力衰竭专业委员会,中华心血管病杂志编辑委员会.中国心力衰竭诊断和治疗指南2018[J].中华心血管病杂志,2018,46(10):760-789.
[6]	Shen S, Ye J, Wu X, et al. Association of N-terminal pro-brain natriuretic peptide level with adverse outcomes in patients with acute myocardial infarction: A meta-analysis[J]. Heart Lung, 2021,50(6):863-869.
[7]	赵良桥,冷永群,卢佳佳,等.心率变异性在冠心病患者和冠心病合并高血压患者中的特点分析[J].中国临床医生杂志,2019,47(3):287-289.
[8]	薛聪,杨晓宇,贾方,等.射血分数保留和射血分数降低的心力衰竭患者心率变异性和心律失常特点及差异分析[J].中国老年学杂志,2021,41(9):1802-1805.
[9]	张经泽,贺世豪,李瑾.冠心病合并慢性心力衰竭病人心率变异性特点及其与病情严重程度的相关性[J].中西医结合心脑血管病杂志,2023,21(22):4198-4202.
[10]	危娜,赵静,邵洁,等. 左卡尼汀联合连续性肾脏替代治疗对CHF病人心功能、鸢尾素、NT-proBNP水平的影响[J]. 中西医结合心脑血管病杂志,2024,22(19):3564-3568.
[11]	包冬英,吴林雁,顾晓青.慢性心力衰竭合并2型糖尿病患者的心率变异性特点及预后[J].临床与病理杂志,2022,42(8):1911-1917.
[12]	张健春,王新康.心率变异性与老年慢性心衰严重程度的相关性分析[J]. 临床心电学杂志,2024,33(3):177-180,185.
[13]	苏朝霞,谢丽锋,龚辉.动态心电图心率变异性时阈参数对老年冠心病合并高血压自主神经功能改变的诊断价值[J]. 标记免疫分析与临床,2024,31(8):1459-1464.
[14]	张聪,安晓飞,杨瑞静,等. 冠心病不稳定型心绞痛病人心率变异性、凝血功能指标与病情严重程度的相关性[J]. 中西医结合心脑血管病杂志,2024,22(18):3380-3383.
[15]	桑园园,王乔,于培,等. 基于心率变异性参数急性心肌梗死患者经皮冠状动脉介入治疗术后院内不良心血管事件预测模型构建与评价[J]. 临床军医杂志,2024,52(8):850-853.
[16]	王旭升,栗思婷,方中.老年急性心肌梗死患者心率变异性、QRS波宽度、QT离散度与不良心血管事件发生关系[J]. 临床军医杂志,2024,52(9):914-916.
[17]	张静,侯少华,徐晶华,等.冠心病合并充血性心力衰竭患者心率变异、甲状腺激素水平及其与病情的相关性[J].西部医学,2021,33(3):392-395.

[1]	. [J]. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(1): 82-86.