神经外科重症监护室呼吸机相关性肺炎危险因素的Meta分析

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Abstract Objective To systematic evaluate the risk factors for ventilator-associated pneumonia (VAP) in neurosurgery ICU. Methods Relevant literatures in CNKI, VIP, Wanfang, PubMed, Embase, The Cochrane library, CBM, Web of Science and other Chinese and English databases were searched by computer until June 2024. Meta-analysis was performed using RevMan5.4 and stata15.0. Results A total of 11 literatures were included, including 9 Chinese ones and 2 English ones, 2022 subjects were included in the study, and 16 possible risk factors were comprehensively evaluated. Smoking, coma, APACHE Ⅱ score, serum albumin <30 g/L, antibiotic use time >3 d, glucocorticoid use, sedative use, hypothermia treatment, mechanical ventilation time≥5 d, and long ICU stay were the risk factors for VAP in neurosurgery ICU (P＜0.05). Early use of antibiotics could reduce the occurrence of VAP (P＜0.05). Conclusions In order to identify and take effective prevention and control measures in the early stage to reduce the occurrence of VAP in neurosurgery ICU, clinical staff should closely monitor the above mentioned risk factors.

Key words： neurosurgery intensive care ventilator associated pneumonia risk factors meta-analysis

Received: 12 November 2024

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	LIN Wei
	SHI Chenyan
	ZHAO Zhuying
	JU Zihan
	ZHAO Fangmin

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LIN Wei,SHI Chenyan,ZHAO Zhuying等. Meta-analysis of risk factors for ventilator-associated pneumonia in intensive care units of neurosurgery[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(4): 290-294.

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https://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR https://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2025/V36/I4/290

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