Analysis of drug resisitance in 158 strains of Staphylococcus aureus
WU Chao1,YAN Kaili2,and DAI Yuanyuan3.
1.Department of Clinical Laboratoy,Anhui Provincial Corps Hospital,Chinese People’s Armed Police Forces,Hefei 230041,China.
2. Anhui Provincial Center for Disease Control and Prevention, Hefei 230061,China.
3. Department of Clinical Laboratoy, Anhui Provincial Hospital, Hefei 230001,China
Abstract: Objective To study the resistance of clinically-isolated Staphylococcus aureus to antimicrobial agents so as to facilitate the rational use of antibiotics. Methods The pathogenic bacteria were evaluated by VITEK32. Drug susceptibility test was carried out by K-B method. The results of 158 strains of Staphylococcus aureus were analysed by WHONET. Results 96 strains of MRSA were detected from 158 strains of Staphylococcus aureus ,which accounted for 60.76%. All the MRSA was resistant to penicillin and ampicillin but was sensitive to vancomycin. The resistance rate of MSSA to penicillin and ampicillin was 69.35% and 67.74%, respectively, and all the MSSA was sensitive to linezolid, quinupristin/dalfopristin and vancomycin. Conclusions Staphylococcus aureus is one of the main pathogens of clinical infection. Analysis of drug resistance of Staphylococcus aureus can guide the clinical use of antibiotics.