Changes in p-selection and glycoprotein Ⅱb/Ⅲa on the surface of platelets between healthy individuals and elderly patients with coronary heart disease(CHD)
XIONG Zhijian1,LI Dandan1,LI Hong2,ZOU Hui1,ZHANG Liping1,and DU Xunhui1.
1.Department of Geriatrics，the General Hospital of PLA，Beijing 100853，China；2. Department of Cardiology，Second Hospital of Nanchang，330003 China
Abstract：Objective To investigate the changes in tyrosine phosphatase(CD148)，P-selection (CD62P) and glyco1protein Ⅱb/Ⅲa(PAC-1) in platelets of elderly patients with coronary heart disease(CHD)．Methods CD148，CD62P and PAC-1 in platelets were analyzed by flow cytometric 3-color immunofluorescence．Results The percentage and MFI of CD62 expression in the platelet membrane in elderly patients with coronary heart disease(CHD) were increased compared with healthy individuals(6.24 vs 0.89，P
熊志坚,李丹丹,李 红,邹 慧,张丽萍,杜寻辉. 冠心病患者与健康老年人血小板表面蛋白酪氨酸磷酸酶、P-选择素及膜糖蛋白Ⅱb/Ⅲa的变化[J]. 武警医学, 2012, 23(9): 763-766.
XIONG Zhijian,LI Dandan,LI Hong,ZOU Hui,ZHANG Liping,and DU Xunhui.. Changes in p-selection and glycoprotein Ⅱb/Ⅲa on the surface of platelets between healthy individuals and elderly patients with coronary heart disease(CHD). Med. J. Chin. Peop. Armed Poli. Forc., 2012, 23(9): 763-766.
2012, Vol. 23 
