磷酸奥司他韦联合板蓝根颗粒治疗甲型H1N1流感疗效观察

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摘要目的观察磷酸奥司他韦联合板蓝根颗粒治疗甲型H1N1流感的临床疗效。方法以我院收治的235例甲型H1N1流感患者为研究对象,随机分为实验组和对照组,其中实验组128例,应用磷酸奥司他韦联合板蓝根颗粒治疗;对照组107例,单用磷酸奥司他韦治疗。对比2组的热程、临床症状、血常规、病毒学检验、住院天数等,从而评价疗效差异。结果入院治疗第3天时,实验组在体温、咳嗽、咳痰、咽痛等临床表现恢复方面均好于对照组(P<0.05);实验组平均住院天数(5.18±3.77)d明显少于对照组平均住院天数(7.86±5.43)d(P<0.05)。结论磷酸奥司他韦联合板蓝根治疗甲型H1N1流感临床疗效明显优于单用磷酸奥司他韦。

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	涂波
	聂为民
	丁鹏鹏
	李丰衣
	陈威巍
	周志平
	张昕
	范荣
	霍丹丹
	赵敏

关键词 ：甲型H1N1流感, 磷酸奥司他韦, 板蓝根颗粒

Abstract：Objective To observe the efficacy of the treatment of influenza A (H1N1) with Oseltamivir phosphate and banlangen granules. Methods 235 in-patients who were diagnosed as having influenza A (H1N1) were divided into trial group and control group. The trial group including 128 patients was administered with oseltamivir phosphate and isatis root granules, and the control group including 107 patients was administered with oseltamivir phosphate only. The temperature period, clinical symptoms, blood routine, viral test and length of stay were compared between the 2 groups. Results After 3 days of treatment, recovery of symptoms including temperature, cough, expectoration and throat sore in the trial group was significantly better than that in control group (P<0.05). The length of stay in the trial group (5.18?3.77 d)was significantly shorter than that in the control group (7.86?5.43 d) (P<0.05). Conclusions The clinical efficacy of treatment of influenza A (H1N1) with oseltamivir phosphate and isatis root granules is better than that using oseltamivir phosphate only.

Key words： influenza A (H1N1) oseltamivir phosphate isatis root granules

收稿日期: 2013-07-02

ZTFLH:

R511.7

基金资助:

国家“十二五”科技重大专项“新发突发传染病中西医结合临床救治研究平台”(2012ZX10004301-007)

通讯作者: 赵敏,E-mail: zhaomin@sina.com E-mail: toby.sky@hotmail.com

作者简介: 涂波,硕士,主治医师,E-mail:toby.sky@hotmail.com

引用本文:

涂波,聂为民,丁鹏鹏,李丰衣,陈威巍,周志平,张昕,范荣,霍丹丹,赵敏. 磷酸奥司他韦联合板蓝根颗粒治疗甲型H1N1流感疗效观察[J]. 武警医学, 2013, 24(6): 465-467. TU Bo,NIE Weimin,DING Pengpeng,LI Fengyi,CHEN Weiwei,ZHOU Zhiping,ZHANG Xin,FAN Rong,HUO Dandan,and ZHAO Min. Efficacy of treatment of influenza A (H1N1) with oseltamivir phosphate and isatis root granules. Med. J. Chin. Peop. Armed Poli. Forc., 2013, 24(6): 465-467.

链接本文:

http://journal08.magtechjournal.com/Jwk_wjyx/CN/ 或 http://journal08.magtechjournal.com/Jwk_wjyx/CN/Y2013/V24/I6/465

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