High-flux hemodialysis combined with L-carnitine in treatment of 56 uremic patients with refractory anemia
REN Yongqiang1,XUE Mei1,and CUI Zhiru2.
1. Department of Nephrology, The Third Hospital of Beijing Municipal Corps,Chinese People’s Armed Police Forces,Beijing 100141,China;
2. Department of Nursing, Inner Mongolia Autonomous Region Corps Hospital, Chinese People’s Armed Police Forces, Hohehot 010040, China
Abstract：Objective To study the effect of high-flux hemodialysis combined with levocarnitine on uremic pationts with refractory anemia. Methods Fifty-six patients with refractory anemia in maintenance hemodialysis were randomly divided into 4 groups: normal group ( 14 cases) underwent conventional hemodialysis, 3 times a week; L-carnitine group (14 cases) was given levocarnitine 1 g on common hemodialysis basis, 3 times a week; high-flux dialysis group (14 cases) received high- flux hemodialysis,3 times a week; high-flux hemodialysis plus L-carnitine group (14 cases) was given levocarnitine 1 g on high-flux hemodialysis basis, 3 times a week. Blood routine and biochemical indicators were examined after treatment for 3 and 6 months, and statistical analysis was made. Results The conventional hemo dialysis group and L-carnitine group had no improvement in anemia; high-flux hemo dialysis group and high-flux hemodialysis plus L-carnitine group improved in anemia, with statistically significant difference, compared with the conventional hemodialysis group (P＜0.05); high-flux hemodialysis combined with L-carnitine group, compared with high-flux hemodialysis group, had remarkable curative effect, with statistically significant difference ( P＜0.05 ). Conclusion High-flux hemodialysis combined with L-carnitine is effective in the treatment of uremic patients with refractory anemia
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2013, Vol. 24 
