A quantitative T2 mapping technique by multi-echo fast spin-echo in cardiac magnetic resonance
LIU Mingxi1,2, ZHANG Wanshi2,ZHANG Ziheng3, MENG Limin2,XU Xianrong4,TIAN Jianwei5,GONG Wanfeng2,and LIU Jie1,2
1.Department of Radiology, Xijing Hospital ,The Fourth Military Medical University, Xi’an 710032,China; 2.Department of CT and MR,Air Force General Hospital, Beijing 100142,China; 3.Advanced Application GE Healthcare China, Beijing 100176,China; 4.Department of Aircrew,Air Force General Hospital,Beijing 100142,China; 5.Department of Cardiology,Air Force General Hospital,Beijing 100142,China
Abstract：Objective To investigate the clinical feasibility and repeatability of a quantitative T2 mapping technique by multi-echo fast spin-echo (MEFSE), and to evaluate the left ventricular myocardial T2 values in different segments. Methods With a 3.0T magnetic resonance (MR) imaging system, according to descriptive research method, cardiovascular magnetic imaging(CMR)was performed in 30 healthy volunteers to investigate the clinical feasibility and repeatability of the quantitative MEFSE T2 mapping technique, combined with Cine and T2WI. T2 values in 17 segments of myocardium and different blood supply areas were measured and compared using one-way ANOVA. The agreement of two radiologists was evaluated by Bland-Altman method and Pearsosn correlation analysis. Results There were differences in the T2 values between some of 17 segmental myocardia (P＜0.01). T2 values were similar in different blood supply areas (F=1.656, P=0.192). Mean myocardial T2 values from the base to the apex were different (F=14.245,P＜0.01): (71.6±7.1) ms (base), (77.3±9.2) ms (middle), (83.0±8.5)ms(apex).According to the Bland—Altman method and Pearson correlation analysis, the measurement of T2 values had a good inter-observer agreement [95% limits of agreement (-6.1,24.8) ms, correlation coefficient r=0.809]. Conclusions Quantitative CMR MEFSE T2mapping technology is feasible and repeatable.Myocardial T2 reference values for the specific CMR setting are provided and they have regional variation.
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2015, Vol. 26 
