Abstract：Objective To approach the effectiveness and diagnostic kit of stroke volume variation(SVV) in assessment of volume expansion responses in patients undergoing liver transplantation(LV).Methods 88 patients undergoing LV were selected randomly, and divided into three groups according to model for end-stage liver disease (MELD). Continuous monitoring for cardiac output was performed by arterial pressure waveform cardiac output (APCO) and mechanical ventilation (VT 8 ml/kg, respiratory rate 10-14 bpm, PEEP<10 cmH2O) was selected after intubation. Fluid therapy of 6% hydroxyethyl starch 130/0.4 8 ml/kg was infused at a rate of 0.4 ml/(kg·min). Following data, including central venous pressure (CVP), cardiac index(CI), SVV and other hemodynamic parameters, were recorded before and after fluid therapy. ΔCI 15% was taken as the criterion of volume expansion. The changing rate of CVP(ΔCVP), SVV(ΔSVV) or CI( ΔCI) was calculated. Statistical analysis of the related parameters was performed.Results Receiver operating characteristic curve (ROC) results showed that the areas under the ROC curve(AUC) for SVV were between 0.8 and 0.9 in the three groups, which were 0.855, 0.857 and 0.867, indicating that the discriminative power of SVV was credible. Moreover, the diagnostic kit was 11.5% when MELD was lower than 15, and 10.5% when it was higher than 15.Conclusions SVV is effective and helpful in assessment of volume expansion response, and it is diagnostic kit is 11.5% or 10.5% according to MELD.
董 兰，安丽娜，刘多辉，李占军，蔡俊刚，谭殿学，陈晓阳，韩曙君. 每搏量变异度指导肝移植手术液体治疗诊断阈值的探讨[J]. 武警医学, 2016, 27(6): 593-596.
DONG Lan, AN Lina, LIU Duohui, LI Zhanjun, CAI Jungang, TAN Dianxue, CHEN Xiaoyang, and HAN Shujun. Diagnostic kit of stroke volume variation in the assessment of volume expansion responses in patients undergoing liver transplantation. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(6): 593-596.
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