Abstract：Objective To compare the short-term effect of corneal endothelium after Intralase and Ziemer femtosecond laser in situ keratomileusis (LASIK).Methods Preoperatively, 1 day, 1 week and 1month after Intralase and Ziemer femtosecond laser in situ keratomileusis, myopia patients were examined by Konan FA-3709P noncontact specular microscope. The mean cell density (CD), coefficient of variation (CV), and hexagonality (6A) of the corneal endothelial cells were determined.Results The changes of CD at 1 day,1 week,1 month after surgery were not statistically significantly different both in Intralase and Ziemer-LASIK and the difference between the two groups was not statistically significant. The CVs in both groups 1 day, 1 week, 1 month after surgery compared with preoperative CV were significantly higher. The differences of CV between the two groups were not statistically significantly different after surgery. The 6As in both groups 1 day, 1 week and 1 month after surgery compared with preoperative 6A decreased significantly. The differences in 6A between the two groups were not statistically significantly different after surgery.Conclusions The CDs of Intralase and Ziemer femtosecond-LASIK groups do not change after surgery. The CVs slightly increase and 6As were slightly decrease after surgery in both groups.
Zhang J, Zhou Y H. Effect of suction on macular thickness and retinal nerve fiber layer thickness during LASIK used femtosecond laser and Moria M2 microkeratome [J]. Int J Ophthalmol,2015,188 (4):777-783.
[2]
Yvon C, Archer T J, Gobbe M, et al. Comparison of higher-order aberration induction between manual microkeratome and femtosecond laser flap creation [J]. J Refract Surg,2015,31(2):130-135.
[3]
Pajic B, Vastardis I, Pajic-Eggspuehler B, et al. Femtosecond laser versus mechanical microkeratome-assisted flap creation for LASIK: a prospective, randomized, paired-eye study [J]. Clin Ophthalmol,2014, 22(8):1883-1889.
[4]
Santhiago M R, Kara-Junior N, Waring G O 4th. Microkeratome versus femtosecond flaps: accuracy and complications[J]. Curr Opin Ophthalmol,2014,25(4):270-274.
[5]
Uzbek A K, Kamburoglu G, Mahmoud A M, et al. Change in biomechanical parameters after flap creation using the Intralase femtosecond laser and subsequent excimer laser ablation [J]. Curr Eye Res, 2011, 36 (4): 614-619.
[6]
Zhou Y, Tian L, Wang N , et al. Anterior segment optical coherence tomography measurement of LASIK flaps: femtosecond laser vs microkeratome [J]. J Refract Surg,2011,27(6):408-416.
[7]
李凤鸣.眼科全书( 上册) [M].北京: 人民卫生出版社,1996: 306.
[8]
Zhang J, Zhou Y, Zhai C, et al. Comparison of 2 femtosecond lasers for laser in situ keratomileusis flap creation [J]. J Cataract Refract Surg,2013, 39(6):922-927.
[9]
Klingler K N, McLaren J W, Bourne W M, et al. Corneal endothelial cell changes 5 years after laser in situ keratomileusis: femtosecond laser versus mechanical microkeratome[J]. J Cataract Refract Surg,2012,38 (12):2125-2130.
[10]
Mu oz G, Albarrán-Diego C, Sakla HF, et al. Effects of LASIK on corneal endothelium using the 15-kHz IntraLase femtosecond laser [J]. J Refract Surg,2011,27(9):672-677.
[11]
Tomita M, Watabe M, Waring GO 4th, et al.Corneal endothelial cell density after myopic intra-LASIK and the effect of AC gas bubbles on the corneal endothelium [J]. Eur J Ophthalmol,2011, 21(4):363-367.
[12]
Choi S K, Kim J H, Lee D. The effect of femtosecond laser lamellar dissection at various depths on corneal endothelium in the recipient bed of the porcine eye [J]. Ophthalmic Surg Lasers Imaging,2010, 41(2):255-260.
[13]
Winkler von Mohrenfels C, Khoramnia R, Lohmann C P. Comparison of different excimer laser ablation frequencies (50, 200, and 500 Hz) [J]. Graefes Arch Clin Exp Ophthalmol,2009, 247(11):1539-1545.
2016, Vol. 27 
