Clinical effect of intercostal nerve blocks using ropivacaine combined with flurbiprofen axeti
YAO Yongzheng1, SHI Chunsheng2, ZHAO Cong3
1.Department of thoracic surgery,Miyun Hospital of Capital Medical University,Beijing 101500,China; 2.Department of anesthesiology,Miyun Hospital of Capital Medical University,Beijing 101500,China; 3.Department of Oncology Shougang Hospital of Peking University,Beijing 100144,China
Abstract：Objective To evaluate the effect of intercostal nerve blocks using ropivacaine combined with flurbiprofen axetil for postoperative analgesia in patients following rib fracture fixation.Methods We retrospectively analyzed 80 patients with rib fracture, who underwent fixation between February 2014 and February 2016. The patients were randomly divided into two groups. Group A received intercostal nerve blocks using ropivacaine combined with intravenous flurbiprofen (40 cases) while Group B used analgesia pumps alone (40 cases). Postoperative pain scores, lung infections, adverse drug reactions and results of postoperative psychological assessment were compared between the two groups.Results Postoperative pain scores and incidence rates of pulmonary complications and adverse drug reactions (lethargy, nausea/vomiting, pruritus and respiratory depression) were significantly lower in Group A. The average scores of pain in the observation group were lower those in the control group (3,5,8,12 h) (P<0.05). Psychological burden scores in Group A were lower than in Group B, while resilience and optimism scores were higher in Group A. There were 2 cases of drowsiness, 3 cases of nausea, 1 case of vomiting, 1 case of skin pruritus, and 1 case of respiratory depression in the observation group, which was better than in the control group.Conclusions Intercostal nerve blocks using ropivacaine combined with flurbiprofen axetil can more effectively reduce postoperative pain, alleviate psychological burden and is worthy of clinical popularization.
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2017, Vol. 28 
