Pathogen Distribution and Risk Factors of Postoperative Abdominal Infections in Patients with Cholelithiasis
CAO Junping1, LI Xia2, XU Li2, SHU Junlian2, LIU Wenxia3, CAO Li1
1. Department of Sterilization and Supply, General Hospital of Armed Police Force, Beijing 100039,China; 2. Department of Pharmacy, General Hospital of Armed Police Force, Beijing 100039,China; 3. Department of Special Diagnosis, the Third Hospital of Beijing Armed Police Force, Beijing 100141, China
Abstract：Objective To investigate the pathogen distribution, antibiotic resistance and risk factors of postoperative abdominal infections in patients with cholelithiasis. Methods 366 patients with cholelithiasis were treated surgically, and 69 of them with postoperative abdominal infections were enrolled in this study. The distribution of pathogens, antibiotic resistance and such risk factors as physical factors or tatrogenic factors were investigated. Results A total of 91 bacterial strains were isolated, including 72 Gram-negative (79.12%), 17 Gram-positive (18.68%) and 2 fungal strains (2.20%). The top four strains were Escherichia coli (37,40.66%), Pseudomonas aeruginosa (19, 20.88%), Klebsiella pneumonia (9, 9.89%) and Enterococcus (9, 9.89%), respectively. None of the Gram-negative strains was resistant to imipenem and all of them showed a high susceptibility to amikacin. None of the Gram-positive strains was resistant to linezolid and all of them showed a high susceptibility to vancomycin. The results showed that some factors, including the gender or age of patients, complications with other diseases, perioperative damage, drainage tubes, and types of postoperative antibiotics,had significant impact on the incidence of postoperative abdominal infections in cholelithiasis patients (P<0.05 or P<0.01). Conclusions Many risk factors are involved in postoperative abdominal infections among patients with cholelithiasis. Some effective interventions should be enforced to reduce the incidence of postoperative infections and postoperative complications in patients.
曹军平, 李霞, 徐丽, 树俊莲, 刘文霞, 曹力. 胆石症术后腹腔感染的病原菌分布及其危险因素分析[J]. 武警医学, 2017, 28(11): 1124-1126.
CAO Junping, LI Xia, XU Li, SHU Junlian, LIU Wenxia, CAO Li. Pathogen Distribution and Risk Factors of Postoperative Abdominal Infections in Patients with Cholelithiasis. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(11): 1124-1126.
Qasaimeh G R, Banihani M N. Laparoscopic cholecystectomy in the elderly and young: a comparative study [J]. Hepatogastroenterology, 2012, 59(113): 22-25.
2017, Vol. 28 
