Comparison of early-onset and late-onset fetal-growth-restriction
XU Guijie1,2 and SHANG Lixin1
1.Department of Obstetrics and Gynecology, the Army General Hospital, Beijing 100700, China; 2.Department of Clinical Medicine, Dalian Medical University, Dalian 116044,China
Abstract：Objective To compare early-onset fetal-growth-restriction(FGR) with late-onset FGR.Methods 161 cases of FGR were retrospectively analyzed, who had been treated at the Army General Hospital between April 2012 and March 2016. According to the first diagnosed pregnancy weeks of FGR, FGR was divided into early-onset group and late-onset group. The main factors and perinatal outcome were analyzed.Results The incidence of gestational hypertension and abnormal vasa umbilicalis among the early-onset were 29.6% and 27.7% respectively, which were significantly higher than that of the late-onset (13.1%, 14.0%). The difference was of statistical significance(P<0.05). 1 min Apgar score (9.25±1.34) and neonatal weight score (2106±635.8) g in the early-onset group were obviously lower than in the late-onset group,(9.74±0.72)and (2418±453.5)g, respectively. The difference of the two scores was of statistical significance(P<0.05). The death rate of perinatal infants in the early-onset group was 13.7%, much higher than that of the late-onset group (0.7%), and the difference was of statistical significance(P<0.05).Conclusions Early-onset FGR is characterized by high complications that lead to poor outcomes. Regular prenatal checkups and punctual treatment of complications can improve the prognosis of the newborn.
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2017, Vol. 28 
