Predictive value of monocyte/high-density lipoprotein cholesterol ratio for postoperative new-onset atrial fibrillation in elderly patients with acute STEMI
LI Beibei1,JIN Zhigeng2,LI Yi2,ZHANG Jiao2,JIA Xiaowei3, and LIU Huiliang1
1.Institute of Cardiology,2.Department of Cardiology,3.Department of Emergency,the Third Medical Center of Chinese PLA General Hospital,Beijing 100039, China
Abstract：Objective To investigate the predictive value of monocyte/high-density lipoprotein cholesterol ratio (MHR) for new-onset atrial fibrillation after PCI in patients with acute ST-segment elevation myocardial infarction. Methods A retrospective analysis was conducted of 181 elderly STEMI patients treated between January 2012 and June 2018 in a hospital. According to the occurrence of atrial fibrillation within 7 days after admission, they were divided into the atrial fibrillation group (31 cases) and non-atrial fibrillation group (150 cases). MHR was compared between the two groups. The ability of MHR to predict new postoperative AF in elderly STEMI patients was evaluated by Logsitic regression analysis and ROC curve assessment. Results (1) Multivariate logistic regression analysis found that MHR, admission heart rate, and LAD were independent risk factors for atrial fibrillation after acute ST-segment elevation myocardial infarction in elderly patients (OR=1.837, 1.160, 1.736, 95% CI: 1.200-2.812, 1.041-1.292, 1.007-2.990, P<0.05).(2) ROC curve analysis suggested that the best cut-off point of new-onset atrial fibrillation after acute STEMI in elderly patients predicted by MHR was 15.81, the predicted sensitivity was 81.8%, the specificity was 90.3%, and the AUC was 0.923 (95%CI: 0.859-0.987; P<0.01). Conclusions MHR is an independent predictor of new-onset atrial fibrillation after acute ST-segment elevation myocardial infarction in the elderly. The mechanism may be related to inflammatory response and oxidative stress.
李贝贝, 金至赓, 李屹, 张蛟, 贾小伟, 刘惠亮. 单核细胞/高密度脂蛋白胆固醇比值对老年急性STEMI患者术后新发心房颤动的预测价值[J]. 武警医学, 2019, 30(1): 15-18.
LI Beibei,JIN Zhigeng,LI Yi,ZHANG Jiao,JIA Xiaowei, and LIU Huiliang. Predictive value of monocyte/high-density lipoprotein cholesterol ratio for postoperative new-onset atrial fibrillation in elderly patients with acute STEMI. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(1): 15-18.
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2019, Vol. 30 
