Maiuolo J, Oppedisano F, Gratteri S, et al. Regulation of uric acid metabolism and excretion[J]. Int J Cardiol,2016,213:8-14.
[2]
Chaudhary K, Malhotra K, Sowers J, et al.Uric acid-key ingredient in the recipe for cardiorenal metabolic syndrome[J].Cardiorenal Med,2013,3:208-220.
[3]
Jin M, Yang F, Yang I, et al.Uric acid, hyperuricemia and vascular diseases[J].Front Biosci,2012,17:656-669.
[4]
Pasalic D,Marinkovic N,Feher-Turkovic L.Uric acid as one of the important factors in multifactorial disorders--facts and controversies[J]. Biochemia Medica,2012,22(1):324-328.
[5]
Bowman G L, Shannon J, Frei B, et al. Uric acid as a CNS antioxidant[J]. J Alzheimers Dis,2010,19:1331-1336.
[6]
MendezH E, SalasP J, RuanoC L, et al. Lower uric acid linked with cognitive dysfunction in the elderly[J]. CNS Neurol Disord Drug Targets,2015,14:564-566.
[7]
Llull L, Laredo C, Renú A, et al. Uric acid therapy improves clinical outcome in women with acute ischemic stroke[J]. Stroke,2015,46(8):2162-2167.
[8]
Tanaka A, Kawaguchi A, Tomiyama H, et al. Cross-sectional and longitudinal associations between serum uric acid and endothelial function in subjects with treated hypertension[J]. Int J Cardiol,2018,1(272):308-313.
[9]
So A, Thorens B. Uric acid transport and disease[J]. J Clin Invest,2010,120:1791-1799.
[10]
Soltani Z, Rasheed K, Kapusta D R, et al Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?[J].Curr Hypertens Rep,2013,15:175-181.
[11]
Ye B S, Lee W W, Ham J H, et al. Alzheimer's Disease Neuroimaging Initiative. Does serum uric acid act as a modulator of cerebrospinalfluid Alzheimer’s disease biomarker related cognitive decline?[J].Eur J Neurol,2016,23(5):948-957.
[12]
Gao X O,Reilly J, Schwarzschild M A, et al. Prospective study of plasma urate and risk of Parkinson disease in men and women[J]. Neurology, 2016, 86(6), 520-526.
[13]
Wen M, Zhou B, Chen Y H, et al. Serum uric acid levels in patients with Parkinson's disease: a meta-analysis[J]. PLoS One,2017,12(3):e0173731.
[14]
Verhaaren B F, Vernooij M W, Dehghan A, et al. The relation ofuric acid to brain atrophy and cognition: the Rotterdam Scan Study[J].Neuroepidemiology,2013,41(1):29-34.
[15]
Hong J Y, Lan T Y, Tang G J, et al. Gout and the risk ofdementia: a nationwide population-based cohort study[J]. Arthritis Res Ther,2015, 28(17):139.
[16]
Engel B, Gomm W, Broich K, et al.Hyperuricemiaand dementia - a case-control study[J]. BMC Neurol,2018,18(1):131.
[17]
Latourte A, Soumaré A, Bardin T, et al. Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study[J]. Ann Rheum Dis,2018,77(3):328-335.
[18]
Cervellati C, Cremonini E, Bosi C, et al. Systemic oxidative stress in older patients with mild cognitive impairment or late onset Alzheimer’s disease[J]. Curr Alzheimer Res,2013, 10:365-372.
[19]
Rinaldi P, Polidori M C, MetastasioA, et al. Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer’s disease[J]. Neurobiol Aging,2003, 24:915-919.
[20]
Kim T S, Pae C U, Yoon S J, et al. Decreased plasma antioxidants in patients with Alzheimer’s disease[J]. Int J Geriatr Psychiatry, 2006, 21:344-348.
[21]
Schrag M, Mueller C, Zabel M, et al. Oxidative stress in blood in Alzheimer’s disease and mild cognitive impairment: a meta-analysis[J].NeurobiolDis,2013, 59:100-110.
[22]
Mullan K, Cardwell C.R, McGuinness B, et al. Plasma antioxidant status in patients with alzheimer’s disease and cognitively intact elderly: a meta-analysis of case-control studies[J].Alzheimers Dis,2018, 62:305-317.
[23]
Desideri G, Gentile R, Antonosante A, et al. Uric acid amplifies Aβ amyloid effects involved in the cognitive dysfunction/dementia:evidences from an experimental model in vitro[J].Cell Physiol,2017,232(5):1069-1078.
[24]
Lee Y H, Song G G. Uric acid and incident dementia: a population-based cohort study[J].Ann Rheum Dis,2018,77(9):e62.
[25]
Khan A A, Quinn T J, Hewitt J, et al. Serum uric acid level andassociation with cognitive impairment and dementia: systematic review and meta-analysis[J].Age Dordr,2016,38(1):16.
2020, Vol. 31 
