Applicability of chest echography and procalcitonin pulmonary infection score(CEPPIS) in patients with ventilator-associated pneumonia(VAP)
ZHU Qian1, DU Juan2, HUANG Xiaoying2, WEN Dalin2, LUO Li2, PENG Xiaoyu2, GAN Ping1, TANG Hao2
1. Department of Intensive Care Unit, Chongqing Municipal Corps Hospital of PAP, Chongqing 400061, China; 2. Wound Trauma Medical Center, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China
Abstract：Objective To evaluate the diagnostic performance of the chest echography and procalcitonin pulmonary infection score(CEPPIS) of patients with ventilator-associated pneumonia(VAP).Methods Patients who were on mechanical ventilation in the intensive care unit (ICU) of Army Medical Center and met the inclusion criteria were included in this study. These patients were divided into the VAP group and control group according to the culture results of bronchial microorganisms (with nosocomial infection and total bacterial colonies>105/ml). Demographic information, clinical features and prognosis were compared via statistical analysis. The CEPPIS and clinical pulmonary infection score(CPIS) were graded using indicators including pulmonary echography, bedside chest radiography, procalcitonin and sputum culture when patients experienced dyspnea or decreased oxygenation. A receiver operating characteristic (ROC) analysis was conducted of CEPPIS, CPIS and procalcitonin to evaluate their diagnostic performance.Results A total of 144 patients were included with 71 patients in the VAP group and 73 in the control group. 93(64.6%) of them were males, and the average age was 54.35 years with a standard deviation of 21.49. The area under curve(AUC) of CEPPIS>5 was 0.846(95%CI:0.775-0.916,P<0.01), greater than 0.713 of CPIS>6 (95%CI:0.625-0.800, P<0.01) and 0.557 of PCT>1 ng/ml(95% CI:0.463-0.652,P=0.048).Conclusions The diagnostic performance of CEPPIS is possibly better than that of CPIS and PCT, but more research is needed to investigate its diagnostic efficiency.
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2020, Vol. 31 
