Abstract：Objective To explore the prognosis and influencing factors of interventional thrombectomy in the treatment of acute ischemic stroke (AIS).Methods The subjects were 106 patients with AIS who received interventional thrombectomy in the Department of Neurology in our hospital between January 2017 and July 2019. The level of prognosis of the included patients was evaluated based on the modified Rankin score three months postoperatively. These patients were divided into the good prognosis group and poor prognosis group to analyze all the clinical data. Furthermore, prognosis-related factors and corresponding risk factors were analyzed while cognitive function and expression levels of serum nerve related factors were compared between the two groups.Results Old age, complications with coronary heart disease, high preoperative levels of serum CRP and Hcy, long recanalization of blocked vessels and partial recanalization 36 h after operation were all risk factors for poor prognosis of interventional thrombectomy for AIS (OR>1, P<0.05). The cognitive function, motor function and language function of the good prognosis group were better than those of the poor prognosis group, with statistically significant difference (P<0.05), but there was no statistically significant difference in the swallowing function between the two groups. In addition, the expression levels of serum nerve related factors in the good prognosis group were better than those of the poor prognosis group, with statistically significant difference (P<0.05).Conclusions AIS patients with good prognosis have better functions and expression levels of serum nerve related factors.Patients who are older, have a long onset-to-treatment time, are complicated with coronary heart disease, have high preoperative serum levels of CRP, Hcy and NIHSS scores, or take a long time have their blocked vessels recanalized or partially recanalized within 36 h of operation deserve more attention, and risk factors should be prevented to improve the prognosis of patients.
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2022, Vol. 33 
