Abstract：Objective To evaluate the clinical value of ventriculopuncture combined with the trans-posterior fossa craniotomy in treatment of intraventricular hemorrhage. Methods In retrospective analysis of clinical data of neurosurgery department from October 2010 to October 2014,there were 80 hypertensive intraventricular hemorrhage patients in the study group (40 cases) and control group (40 cases). The study group patients were treated with ventriculopuncture combined with trans-posterior fossa craniotomy and urokinase fibrinolytic therapy; the control group patients were treated with ventriculopuncture and urokinase fibrinolytic therapy. And analysis of their prognosis was made. Results The hematoma in the lateral ventricle,the third ventricle and the fourth ventricle were removed postoperatively,the removal time of hematoma in study group was (5±2) days, compared with (9±3) days in the control group, with statistically significant difference (P<0.01); and the mortality was 5% in the study group,compared with 22.5% in the control group, the difference was significant (P<0.01). The activities daily living score (ADL) in surviving patients improved in the following 6 months(P<0.05). Conclusions Ventriculopuncture combined with trans-posterior fossa craniotomy in treatment of intraventricular hemorrhage is effective, which significantly reduces the mortality rate and improves the prognosis of patients.
Chi F L, Lang T C, Sun S J, et al. Relationship between different surgical methods, hemorrhage position, hemorrhage volume, surgical timing, and treatment outcome of hypertensive intracerebral hemorrhage[J]. World J Emerg Med,2014,5(3): 203-208.
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Strahle J, Garton H J, Maher C O, et al.Mechanisms of hydrocephalus after neonatal and adult intraventricular hemorrhage[J]. Transl Stroke Res,2012,3(1): 25-38.
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Ziai W C, Tuhrim S, Lane K, et al. A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR Ⅲ)[J]. Int J Stroke, 2014, 9(4): 536-542.
2015, Vol. 26 
