Abstract：Objective To investigate the Stenotrophomonas maltophilia induced noxocomial acquired pneumonia in elderly tumor patients,its clinical characteristics and risk factors, and to guide clinical diagnosis and treatment. Methods Thirty-four elderly patients with stenotrophonas maltophilia induced nosocomial acquired pneumonia admitted in 306th Hospital Blood Oncology Department from August 2007 to January 2007 were recruited as study group, and 102 elderly tumor patients without nosocomial acquired pneumonia admitted in the same period were as control group; their clinical data were retrospectively analyzed.Results Of 34 elderly tumor patients with such pneumonia, 24 were male , 10 female, aged 60 to 91 years old, average age 77±11. All patients had accompanied basic diseases, fever(mainly moderate). Accompaniod fungal infection was common in patients with high fever or with multi-resistant, generic drug resistant bacterial infections. All patients had respiratory symptoms, chest X-ray or CT of the lung inflammation change.From more than 82.4% of patients, 2 strains of pathogenic bacteria were isolated. 50% of patients had multi-resistant, generic drug resistant bacteria infections. High proportion of patients had lung cancer and lymphoma. More than 2 kinds of antibiotics were used, 7 patients(20.6%) received antifungal therapy at the same time, 28 patients(82.4%) used carbabenems antibiotic treatment, 17 patients (50%), used quinolones. Long length of hospital stay, chemotherapy, and anemia were risk factors to elderly tumor patients with nosocomial acquired pneumonia.Conclusion For elderly tumor patients with basic diseases, accompanied by fever and respiratory symptoms ,we should be alert to Stenotrophomonas maltophilia induced nosocomial acquired pneumonia.Long duration of hospital stay, chemotherapy and anemia are the risk factors contributory nosocomia acquired pneumonia in elderly patients with tumor.
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2016, Vol. 27 
