Efficacy of irrigation combined with closed negative pressure drainage and traditional lavage drainage in the treatment of incision infections after limb fracture surgery
GUO Changqing
Department of Orthopedics, People’s Hospital of Gu’an County,Gu’an 065500,China
Abstract:Objective To compare the clinical effect of lavage combined with closed negative pressure drainage and that of traditional irrigation drainage.Methods Forty-eight patients with postoperative infections after surgery of limb fractures who were treated between January 2015 and January 2016 at Gu’an County People’s Hospital were selected, who were equally divided into two groups using the random number table method. Patients in the treatment group were treated with lavage combined with closed negative pressure drainage while the control group was treated with traditional lavage and drainage. The culture-negative rate1 and 2 weeks after drainage and the recurrence of infections within 3 months were observed in both groups. The duration of use of antibiotics, extubation time, wound healing time and hospital stay of the two groups were compared. The Neer score was observed 6 months after operation.Results After the first and second week, the negative rate of bacterial culture in the treatment group was higher than that in the control group with statistically significant difference (P<0.05).There was one case of recurrence in the treatment group (4.17%) and two cases in the control group (8.33%) within three months. No statistically significant difference was found between the two groups. The antibiotic dose duration, extubation time, healing time and hospital stay of the treatment group were shorter than those of the control group, with statistically significant difference (P<0.05). The Neer score of the treatment group 6 months after operation was better than that of the control group, and the difference was statistically significant between the two groups (P<0.05).Conclusions Irrigation combined with closed negative pressure drainage technology can facilitate the control of infections after fracture of limbs, promote wound healing and improve the Neer score.
郭长青. 四肢骨折术后切口感染灌洗结合封闭负压引流疗效[J]. 武警医学, 2017, 28(9): 893-896.
GUO Changqing. Efficacy of irrigation combined with closed negative pressure drainage and traditional lavage drainage in the treatment of incision infections after limb fracture surgery. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(9): 893-896.
Wang X, Yang F, Guan Z,et al. Mechanism of vacuum sealing drainage therapy attenuating ischemia-reperfusion injury of skeletal muscle in rabbit[J]. Zhonghua Wai Ke Za Zhi, 2016 ,54(4):292-296.
Semrau K E, Herlihy J, Grogan C,et al.Safety, effectiveness and economic aspects of maggot debridement therapy for wound healing[J]. Lancet Glob Health, 2016 ,4(11):e827-e836.
[6]
Momaya A M, Hlavacek J, Etier B,et al.Risk factors for infection after operative fixation of Tibial plateau fractures[J]. Injury,2016,47(7):1501-1505.
[7]
Liu X, Liang J, Zao J, Quan L, et al.Vacuum Sealing Drainage Treatment Combined with Antibiotic-Impregnated Bone Cement for Treatment of Soft Tissue Defects and Infection[J]. Med Sci Monit, 2016 ,22:1959-1965.
[8]
Li R G, Ren G H, Tan X J, et al.Free flap transplantation combined with skin grafting and vacuum sealing drainage for repair of circumferential or sub-circumferential soft-tissue wounds of the lower leg[J]. Med Sci Monit, 2013 ,19:510-517.
[9]
Wang J, Zhang H, Wang S.Application of vacuum sealing drainage in the treatment of internal fixation instrument exposure after early postoperative infection[J]. Minerva Chir, 2015 ,70(1):17-22.
Penn J G, Murray C K, Wenke J C. Comparison of the antimicrobial effect of chlorhexidine and saline for irrigating a contaminated open fracture model[J]. J Orthop Trauma, 2012 ,26(12):728-732.