Influence of one lung ventilation on cardiac function and hemodynamic status
HOU Lingdi1, 2, LI Zhanjun2, LI Shengnan2, YANG Shufeng2, NING Xinyu2
1.The Graduate School of Jinzhou Medical Univercity, Jinzhou 121001, China; 2. Department of Anesthesiology, General Hospital of Chinese People’s Armed Police Force, Beijing 100039,China
Abstract:Objective To evaluate the effect of one lung ventilation (OLV)on patient’s cardiac function and hemodynamic status during thoracic surgery by FloTrac/Vigileo system.Methods A total of 101 class Ⅰ-Ⅱ adult patients by American Society of Anesthesiologists (ASA) who had undergone the double lumen endotracheal intubation in the lateral position during thoracic surgery were enrolled in this study. Each hemodynamic parameter was recorded by FloTrac /Vigileo system at different time points that included the time before anesthesia induction(T0), 5 min into intubation in the supine position by two lung ventilation (T1) , 5 min after the lateral position by two lung ventilation(T2),5 min after OLV (T3) ,10 min after OLV(T4) , 30 min after OLV(T5), 60 min after OLV(T6) ,after lung inflation (T7),and 5 min after the supine position by two lung ventilation (T8).Results MAP and HR were higher at T0 than at T2 (P<0.05).SVR was higher at T1 than at T6 (P<0.05).MAP, HR, CO and CI were lower at T1、T3 than at T4 (P<0.05). MAP was higher at T2 than at T4, and HR was lower at T3 than at T4 (P<0.05). SpO2 was the lowest at T5 (P<0.05). HR was higher at T6 than at T7, while MAP and SV were lower at T6 than at T7 (P<0.05).Conclusions After one lung ventilation, patients can experience transient hemodynamic instability, for MAP, HR, CO and CI tend to increase while SpO2 and SVR tend to decrease compared with double lung ventilation. However, as the one lung ventilation continues, the indicators gradually become stable.
侯领弟, 李占军, 李胜男, 杨树峰, 宁新宇. 单肺通气对心功能和血流动力学的影响[J]. 武警医学, 2017, 28(10): 1005-1007.
HOU Lingdi, LI Zhanjun, LI Shengnan, YANG Shufeng, NING Xinyu. Influence of one lung ventilation on cardiac function and hemodynamic status. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(10): 1005-1007.
Biancofiore G, Critchley L A, Lee A, et al . Evaluation of a new software version of the FloTrac /Vigileo( version 3. 02) and a comparison with previous data in cirrhotic patients undergoing liver transplant surgery[J].Anesth Analg,2011,113(3):515-522.
[2]
Yun D G, Han J I, Kim D Y, et al . Is small tidal volume with low positive end expiratory pressure during one-lung ventilation an effective ventilation method for endoscopic thoracic surgery?[J]. Korean J Anesthesiol, 2014, 67(5):329-333.
[3]
Kammerer T,Speck E,Dossow V.Anesthesia in thoracic surgery[J].Anaesthesist,2016,65(5):397-412.
Karzai W, Schwarzkopf K. Hypoxemia during One-lung VentilationPrediction, Prevention, and Treatment[J]. Anesthesiology, 2009, 110(6):1402-1411.
[6]
Brassard C L, Lohser J, Donati F, et al . Step-by-step clinical management of one-lung ventilation: continuing professional development[J]. Can J Anaesth, 2014, 61(12):1103-1121.
[7]
Jung D M, Ahn H J, Jung S H, et al . Apneic Oxygen Insufflation Decreases the Incidence of Hypoxemia During One-lung Ventilation in Open and Thoracoscopic Pulmonary Lobectomy: A Randomised Controlled Trial[J]. Thorac Cardiovasc Surg,2017,154(1):360-366.
[8]
Wang M, Gong Q, Wei W. Estimation of shunt fraction by transesophageal echocardiography during one-lung ventilation[J]. Clin Monit Comput, 2015, 29(2):307-311.
Bruin G. Lung re-inflation after one-lung ventilation for thoracic surgery: importance of clamping the dependent lung[J]. Can J Anaesth, 2014, 61(11):1061-1061.
[11]
Lange R A, Katz J, Mcbride W. Effects of supine and lateral positions on cardiac output and intracardiac pressures[J]. Am J Cardiol, 1988, 62(4):330-333.