Application of SD-Ag to wound healing in second degree burned patients
SHA Deqian1, ZHANG Weiwei2, LIU Hongqi1, ZHU Yaqin3
1.Department of Burn and Plastic Surgery,Affiliated Hospital of Logistics College of Chinese People’s Armed Police Force,Tianjin 300162,China; 2.Department of Second the south tower, General Hospital of Chinese People’s Armed Police Force,Beijing 100039,China ; 3.Yantai Sanatorium of Chinese People’s Armed Police Force, Yantai 264003, China
Abstract：Objective To observe the curative effect of sulfadiazine silver suspension in the treatment of burn wounds.Methods One hundred and seventy-two burn patients were selected between January 2015 and October 2017, whose wounds met the clinical diagnostic criteria for second degree burns.The patients were admitted 24 hours after injury and were randomly divided into two groups that were respectively treated with sulfadiazine silver suspension and Jingwanhong after hospitalization. Meanwhile, bacteriological culture was taken to observe the healing time of the wounds, the bacterial negative rate, and the duration of antibiotic use in the two groups.Results In the sulfadiazine silver suspension group,the shallow second degree burns were all healed within 10 to 12 days after injury, with an average healing time of (11.8±2.3) days, while the deep second degree burns healed in 19 to 28 days, with an average healing time of (23.5±3.2 )days.Antibiotics were used for an average of 7 days.In the Jingwanhong group, 26 patients had wound infections and wound redness. Deep second degree wounds deepened in 7 cases but healed after skin graft. Excluding the 7 cases of wound infections that were cured after skin graft, the average healing time of shallow second wounds was (14.1±2.4)days, compared with(27.8±3.5)days for deep second wounds. The average duration of antibiotic use was (10.8±0.6)days.The number of bacteria in the wound, the duration of antibiotic use and the time taken by wound healing were significantly smaller or shorter than those of patients treated with Jingwanhong.Conclusions Compared with Jingwanhong, sulfadiazine silver suspension can significantly increase the anti infection effect, reduce the number of bacteria in the wound, and facilitae the healing of wounds, which is worthy of wider application.
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2018, Vol. 29 
