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| Efficacy of Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid in treatment of verruca plana |
| CHEN Wei 1，LUO Wei 2， and YANG Lihong 3. |
| 1. Department of Dermatology, 3. Department of Physiotherapy, Third Hospital of Beijing Municipal Corps, Chinese People’s Armed Police Forces, Beijing 100141，China；2. Department of Dermatology, General Hospital of Air Force, PLA, Beijing 100036, China |
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Abstract Objective To study the clinical efficacy of Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid in the treatment of verruca plana. Methods One hundred and eight patients with verruca plana were randomly divided into two groups：the treatment group (56 patients)and the control group (52 patients). Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid were given to the treatment group while the control group was treated with Zilan Decoction alone．Four weeks later，the therapeutic efficacy was analyzed after completion of the therapy. Results The curative rate was 89.29% in the treatment group and 69.23% in the control group. The total effective rate was 96.43% in the treatment group and 82.69% in the control group. There was statistically significant difference in the curative rate and total effective rate between the two groups. The results of statistics for the two groups were χ 2=6.69, P <0.05 and χ 2=5.56, P <0.05, separately. Conclusions Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid phototherapy is more effective than Zilan Decoction alone in the treatment of verruca plana.
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Received: 14 September 2011
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吴志华.皮肤科治疗学［M］.北京:科学出版社,2006:155.［2］张志礼.张志礼医话验案精选［M］.北京:人民军医出版社,2009:193.［3］国家中医药管理局.中医病症诊断疗效标准［M］.南京:南京大学出版社,1994:145.［4］王进波,叶珊.基因芯片检测人类乳头瘤病毒23亚型的应用评价［J］.中国皮肤性病学杂志,2007,21(2):78-81.［5］雷山川.自体组织蛋白与卡介菌多糖核酸联合治疗扁平疣［J］.中国皮肤病学杂志,2005,19,(1):25-26.［6］张莉,赵庆利,江丽，等.左旋咪唑、潘生丁联合治疗扁平疣疗效观察［J］.中国麻风皮肤病杂志.2005,21(7):570-571.［7］陈曙光,刘平,李渊，等.阿维A治疗掌跖脓疱病50例［J］.中华皮肤科杂志,2006,39,(3)：180 .［8］汪晶贤,刘学东,王丹彧.斯奇康辅助治疗扁平疣104例疗效观察［J］.当代医学,2008,14,(24):171.
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吴志华.皮肤科治疗学［M］.北京:科学出版社,2006:155.［2］张志礼.张志礼医话验案精选［M］.北京:人民军医出版社,2009:193.［3］国家中医药管理局.中医病症诊断疗效标准［M］.南京:南京大学出版社,1994:145.［4］王进波,叶珊.基因芯片检测人类乳头瘤病毒23亚型的应用评价［J］.中国皮肤性病学杂志,2007,21(2):78-81.［5］雷山川.自体组织蛋白与卡介菌多糖核酸联合治疗扁平疣［J］.中国皮肤病学杂志,2005,19,(1):25-26.［6］张莉,赵庆利,江丽，等.左旋咪唑、潘生丁联合治疗扁平疣疗效观察［J］.中国麻风皮肤病杂志.2005,21(7):570-571.［7］陈曙光,刘平,李渊，等.阿维A治疗掌跖脓疱病50例［J］.中华皮肤科杂志,2006,39,(3)：180 .［8］汪晶贤,刘学东,王丹彧.斯奇康辅助治疗扁平疣104例疗效观察［J］.当代医学,2008,14,(24):171.
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