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| Detection of tinnitus patients with PET-CT clinical analysis |
| GU Dongsheng1,CAO Xiaoping1,LIU Taifeng2,HUANG Aiping1,CHEN Yuwu1,YU Dangfan2,and WANG Tiansheng1. |
1.Department of Otolaryngology ＆ Head-Neck Surgery,
2. PET/CT Center,Zhejiang Provincial Corps Jiaxing Hospital, Chinese People’s Armed Police Forces, Jiaxing 314000, China |
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Abstract Objective To study the central metabolic characteristics and the change in central metabolism in patients with tinnitus undergoing masking therapy. Methods Select Five subjects with normal hearing tinnitus and, at the same time, twenty normal people who have undergone PET-CT examination were recruited. The tinnitus patients’ standardized uptake values(SUV) of right and left transverse temporal gyri and hippocampal gyrus were compared with those in normal subjects. SUV of 5 tinnitus patients were compared on each side of transverse temporal gyri and hippocampal gyrus before masking therapy with those having masking therapy. Results Of 5 cases of tinnitus, transverse temporal gyri and hippocampal gyrus metabolism was asymmetric in 4 cases, and the left metabolism was significantly higher than the right side on all performance. The other one was normal. All metabolism in normal control group was symmetrical. Between the two groups, the asymmetric indexes were significantly different (P＜0.01). And in 5 cases of tinnitus with masking therapy, SUV of auditory cortex with sound in one side masking therapy was higher than that without sound, each side before masking therapy and after had significant difference (P< 0.01). Conclusions The high metabolism of the left transverse temporal gyri and hippocampal gyrus is associated with tinnitus. Masking therapy has curative efficacy and may affect the metabolic level of auditory cortex functional area.
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Received: 15 November 2012
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2013, Vol. 24 
