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Comparison of effect of three radiation doses for early stage nasal NK/T cell lymphoma |
WU Lizhou,LIU Hanshan,and CAI Wei |
Department of Radiochemotherapy,Jiangsu Provincial Corps Hospital,Chinese People’s Armed Police Forces,Yangzhou 225003,China |
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Abstract Objective To study the effects of different radiotherapy doses on the early stage nasal NK/T cell lymphoma. Methods 64 patients with early stage nasal NK/T cell lymphoma undergoing radiotherapy were divided into <50 Gy group(n=20), 51-60 Gy group(n=24) and >60 Gy group(n=20), all groups were observed and their local control rate and survival rate of 5 years were compared. Results The total local control rates in the three groups were 68.5%, 82.5% and 72.2% respectively. There was significant difference in the local control rate and survival rate of 5 years between<50 Gy group and the other two groups (51-60 Gy and >60 Gy group) (P<0.05), but the differences between the two groups were not statistically significant. Conclusions 51-60 Gy doses of radiation can guarantee good local control rate, improve overall survival rate. The choice of radiation doses to 50 Gy in patients with early stage nasal NK/T cell lymphoma is appropriate, with clinical recommendations.
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Received: 27 July 2013
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