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| Measurement of uncertainty of catalpinoside in Ganmainingxin Capsule |
| LIU Jiyang1, WANG Xiaofei1, YU Ling1, YAO Hongwei1, HU Hao1, and CHAI Jiangping2 |
1. Institute for Drug Control of People’s Armed Police Force,Beijing 102613,China;
2. Guang Anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China |
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Abstract Objective To find out the effect factors of uncertainty by analyzing the uncertainty of measurement in determination of catalpinoside by HPLC and provide the evidence to evaluate the measurement. Methods The Catalpinoside in Ganmainingxin Capsules was determined by HPLC. The causes and effects were simplified and uncertainty was appraised. Results The uncertainty result was 2.70% and the result of content was(1.17±0.063)mg/g. Conclusions The mathematic model established is suitable for uncertainty analysis of catalpinoside by HPLC.
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Received: 24 April 2015
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| [1] |
国家质量监督检验检疫总局. JJF1135-2005 化学分析测量不确定度评定[S]. 北京: 中国计量出版社, 2005.1-8.
|
| [6] |
李慎安. JJF1059-1999 《测量不确定度评定与表示》讨论之六 测量仪器不确定度[J]. 中国卫生检验杂志, 2006,16(4): 39-40.
|
| [2] |
中国合格评定国家认可委员会. 声明检测或校准结果及与规范符合性的指南[M]. 北京:中国合格评定国家认可委员会,2009:4-7.
|
| [3] |
孙 莉. HPLC 法测定炔诺酮片含量及含量均匀度的不确定度分析[J]. 中国药房, 2009, 20(4):294-296.
|
| [4] |
车晓彦,伍丕娥,周 娟,等. 麦冬药材TLC及HPLC 特征图谱研究[J]. 药物分析杂志, 2012,32(12):2263.
|
| [5] |
杨仕林,李小刚,谢 云.RP-HPLC法测定天王补心丸中梓醇的含量[J].中国药方,2012,23(24):2289-2290.
|
| [6] |
李慎安. JJF1059-1999 《测量不确定度评定与表示》讨论之六 测量仪器不确定度[J]. 中国卫生检验杂志, 2006,16(4): 39-40.
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2015, Vol. 26 
