对烧伤患者检测血清降钙素原和尿肾损伤分子1的临床意义

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Abstract Objective To study the meaning of serum PCT and urine KIM-1 detection for urine kidney damage in patients with different degree burns. Methods 123 burn patients admitted from January - December 2013 in this hospital were divided intomild, medium and severe burn groups. 40 subjects andergoing physical examination during the same period in this hospital were selected as controls. Generally signs (body temperature, heart rate, breathing), CRP, BUN, Cys-C, PCT and KIM - 1 levels were compared between the two groups. Results Compared with healthy control group, mild-to-severe burn group had no significant difference in terms of body temperature, heart rate and respiration (P＞0.05). Mild-to-severe burn group, compared to healthy group, had statistically significant difference in WBC levels (11.5±2.7,12.7±3.3,17.9±5.6,P＜0.05), but had no remarkable difference compared with mild-to-moderate burn group that the severe burn group and mild-to-moderate burn group havd statistically significant difference. The CRP level in mild-to-severe burn group had obvious difference compared with healthy group (P＜0.05) while no obvious difference among the three burn groups (P＞0.05). As to BUN measurement, only severe burn group had difference with other groups (P＜0.05). The difference in the Cys-C levels in moderate-to-severe burn group compared with healthy group had statistically significant differcace (P＜0.05). All differences in terms in PCT and KIM-1 levels of burn groups compared with healthy group had statistically significant difference. And the differences in PCT and KIM-1 levels among different burn groups (mild-to-moderate, moderate-to-severe, mild-to-severe) had statistically significant difference (P＜0.05). Conclusions The serum PCT and KIM-1 can be used in different degree burn patients with sepsis in the early detection, which is of great significance.

Key words： serum PCT urine KIM-1 burns

Received: 02 December 2014

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	Articles by authors
	LIU Yuanyuan
	ZHENG Tianliang
	HAN Zhongxue
	and ZHOU Ting

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LIU Yuanyuan,ZHENG Tianliang,HAN Zhongxue等. Meaning of serum PCT and urine KIM-1 detection for urine kidney damage in patients with different degree burns[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(12): 1213-1215.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I12/1213

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