儿童视网膜母细胞瘤个体化综合治疗的临床分析

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Abstract Objective To analyze the effect and existing problems of individualized comprehensive treatment of children’s retinoblastoma (RB). Methods Based on the general condition and clinical staging of 59 child patients (75 eyes) with RB, their curative effect and existing problems of individualized comprehensive treatment were analyzed. Results RB children’s initial symptoms were common: leukocoria in 35 cases (60%), strabismus in 12 cases (20%), conjunctival congestion in 6 cases (10%), decreased vision in 3 patients (5%), exophthalmus in 3 cases (5%). In 59 children with RB, their intraocular stage three-year survival rate was 90% (43/48), extraocular period survival rate was 45% (5/11), overall survival rate was 81% (48/59). Of the 75 affected eyes, the total preserved eye rate was 41.3% (31/75), including A - C stage preserved eye rate of 100%, D stage preserved eye rate of 68% (17/25), E stage preserved eye rate of 13.8% (4/29). Two extraocular RB patients because of large size of tumor could not do surgery, nine extraocular stage patients underwent successful surgical removal of the tumor, the surgical resection rate was 82%. Conclusions Individualized comprehensive treatment of RB can improve the survival rate of children and the recovery rate of eye, but the eye removal rate in E period children is still high. The management of child patients with extraocular period RB is important and difficult.

Key words： retinoblastoma individualized comprehensive treatment

Received: 31 October 2014

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R730.5

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	Articles by authors
	WANG Jun
	SUN Yanfeng
	MIAO Lixia
	YUAN Hailian
	LI Yanshan
	LIU Hongyan
	LIU Qiuling

Cite this article:

WANG Jun,SUN Yanfeng,MIAO Lixia等. Clinical analysis of individualized comprehensive treatment of child retinoblastoma[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(3): 232-235.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I3/232

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