息肉标本预处理方法对高分辨率显微内镜成像效果的影响

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Abstract Objective To verify the effect of high-resolution microendoscopic imaging and to compare the effects of different pretreatment methods for colon polyps specimens in high-resolution microendoscopic imaging and the accuracy of the diagnosis of disease. Methods In vitro specimens from 90 patients with colon polyps were randomly divided into three groups: using saline (group A), saline plus mucus removing agent (group B), saline, and mucus removing agent plus hypertonic glucose solution (group C) to wash and high-resolution microscopic imaging was made for pretreated specimens of colon polyps and then for pathological examination.The picture quality of the three groups was analyzed. Results The high-resolution microscopic images are 900 for specimens in each polyp, high-quality images in group A were 317 and high quality rate was 35.2%; high-quality images in group B were 493 and high quality rate was 54.8%; and high-quality images in group C were 564 and high quality rate was 62.7%, the difference was statistically significant (P<0.05).Compared with the pathological examination, group A showed simultaneous diagnosis of adenomatous polyps in 9 cases, 8 cases of non-adenomatous polyps, with diagnostic accuracy of 56.7%;group B showed simultaneous diagnosis of adenomatous polyps in 13 cases, non-adenomatous polyps in 7 cases, with diagnostic accuracy of 66.7%; and group C showed simultaneous diagnosis of adenomatous polyps in 12 cases, non-adenomatous polyps in 15 cases, with diagnostic accuracy of 90.0%. The overall accuracy of high-resolution microendoscopy in diagnosis of colon polyps was 71.1%. In Group C, compared with group A, and compared with group B. The difference was statistically significant (P<0.05). Conclusions High-resolution microendoscopy has good imaging results for polyp specimens after pretreatment. It can improve the picture quality and diagnostic accuracy before imaging using saline combined with mucus removing agent and hypertonic glucose solution.

Key words： colon polyps high resolution microendoscopy mucus removing agent hypertonic glucose diagnosis

Received: 11 January 2015

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	TAN Tao
	QU Yawei
	LIU Haifeng

Cite this article:

TAN Tao,QU Yawei,LIU Haifeng. Affect of different pretreatment methods of polyp specimens on high-resolution microendoscopic imaging[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(4): 343-346.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I4/343

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