成年人血清25羟基维生素D水平调查

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Abstract Objective To investigate serum 25(OH)D₃ level of adults and its correlations with the season, gender, BMI, calcium, phosphorous and PTH of physical examinees in Beijing.Methods The levels of serum 25(OH)D₃ and PTH data of 825 physical examinees were acquired by Electro-Chemiluminescence Immunoassay (ECLI). The levels of 25(OH)D₃ were analyzed in connection with the season, gender and BMI. Linear regressions were used to study the relationships between 25(OH)D₃ and other variables.Results Serum 25(OH)D₃ followed a skewed distribution with a median of 12.31(8.57,16.70)ng/ml. In our study, 397 samples (accounting for 48.1% of total samples) were diagnosed as severe deficiency of 25(OH)D3 (<12 ng/ml) while another 314 samples (38.1%) as moderate deficiency of 25(OH)D₃ (12-20 ng/ml). The level of serum 25(OH)D₃ was significantly higher in summer and autumn and was at the bottom in spring.There was significant difference in the level of serum 25(OH)D₃ between males and females, with the level among men (aged below 60) evidently higher than among women (P＜0.01). Serum 25(OH)D₃ level was significantly lower among obese and overweight women than among women of normal weight (P＜0.05). Female serum 25(OH)D₃ level was negatively correlated with BMI (r=-0.143,P=0.015), so was sample 25(OH)D₃ with PTH (r=-0.234,P＜0.01).Conclusions Serum 25(OH)D deficiency is common among physical examinees in Beijing. It is recommended that specific vitamin D supplementation for different seasons, sex and BMI be initiated for primary prevention.

Key words： serum25(OH)D₃ sex season BMI

Received: 07 November 2016

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	Articles by authors
	CHENG Xiaoqiu
	DENG Xiaowei
	YUAN Jiajing
	LIU Xia
	and WANG Yahan

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CHENG Xiaoqiu,DENG Xiaowei,YUAN Jiajing等. A survey on serum 25(OH)D₃ level of adults[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(6): 582-586.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2017/V28/I6/582

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