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Effect of group B streptococcal infection on pregnancy outcomes in late pregnancy |
GAO Fei, WANG Yahui, ZHANG Minjie, ZHAO Xia, and ZHANG Xue |
Department of Obstetrics and Gynecology, Maternal and Child Health Care Hospital of Baoding, Baoding 071000, China |
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Abstract Objective To investigate the effect of group B streptococcal infection on pregnancy outcome in late pregnancy.Methods The data of 1455 cases of pregnant women in our hospital were collected from 2017-11 to 2018-03.GBS test was performed at 35~37 weeks of pregnancy, it was divided into GBS positive group and GBS negative group according to whether that GBS infection occurred. The GBS positive group was divided into treatment group A (oral antibiotic 7 days at 35-37weeks,except for conventional treatment at birth or after premature rupture of membranes) and treatment group B (routine treatment at birth or after premature rupture of membranes) according to the different treatment methods.Pregnancy outcomes were compared between treatment groups A and B, GBS positive group and GBS negative group.Results (1)The positive rate of GBS was 7.9% (115/1455) in 1455 pregnant women;(2)The incidence rates of premature rupture of membranes, premature delivery, intrauterine infection, cesarean delivery, amniotic fluid turbidity, postpartum hemorrhage, pneumonia of newborn, and neonatal infections in the GBS positive group were statistically significantly higher than those in the GBS negative group (P<0.05); (3)There was no statistically significant difference between the treatment group A and the treatment group B in the all observation indicators.Conclusions GBS infection will easily result in premature rupture of membranes and other adverse pregnancy outcomes. In order to avoid overuse of antibiotics, prophylactic treatment for streptococcus B carriers should be carried out at the time of labor or premature rupture of membranes, so as to achieve satisfactory infection control effect.
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Received: 12 June 2018
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