右美托咪定预防腹腔镜子宫肌瘤切除术后恶心呕吐的效果

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Abstract Objective To study the effect of subclinical doses of dexmedetomidine on the prevention of nausea and vomiting after laparoscopic myomectomy.Methods One hundred and twenty patients scheduled to undergo laparoscopic myomectomy between June 2016 and December 2017 were selected. These patients were randomly divided into three groups: the dexmedetomidine group, the ramosetron group , and the metoclopramide group. In the dexmedetomidine group, the background dose was 0.4 μg/kg, and infusion was completed slowly (3-5 min). The ramosetron group was given remerstom 0.3 mg 30 min before the end of the operation. The metoclopramide group was given metoclopramide 20 mg 30 min before the end of surgery. The incidence of nausea and vomiting was observed in these three groups of patients 0-1 h, ＞1-3 h, ＞3-6 h, ＞6-12 h after extubation.Results There was no statistically significant difference in the incidence of postoperative nausea and vomiting between the three groups 3 h after surgery, but the incidence of postoperative nausea and vomiting in the dexmedetomidine group and the ramosetron group was significantly lower than that in the metoclopramide group (P<0.05).Conclusions Intravenous injection of some dose of dexmedetomidine before induction and intraoperative maintenance of small-dose infusion or a dose of ramosetron or metoclopramide (wintin 3 hour) 30 min before the end of surgery can all effectively prevent nausea and vomiting induced by laparoscopic hysteromyoma resection three hours after surgery. Dexmedetomidine and ramosetron are more effective than metoclopramide.

Key words： dexmedetomidine resection of the hysterectomy nausea and vomiting

Received: 20 January 2018

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	Articles by authors
	JIANG Ye
	WANG Qingxiu
	and HE Hong

Cite this article:

JIANG Ye,WANG Qingxiu,and HE Hong. Clinical observation of dexmedetomidine in prevention of nausea and vomiting after laparoscopic hysteromyomectomy[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(5): 473-475.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2018/V29/I5/473

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