营养干预对胃部肿瘤化疗患者生活质量及依从性的影响

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Abstract Objective To investigate the effect of nutritional intervention on quality of life and chemotherapy compliance of patients with relapsed or metastatic gastric cancer and with PG-SGA scores ranging from 2 to 3 during chemotherapy.Methods A total of 86 patients with recurrent or metastatic gastric cancer who had got 2-3 points according to the PG-SGA method and received treatment between June 2015 and May 2017 were enrolled in this study, who were randomly divided into the observation group and control group (n=43). The control group was treated with diet combined with oral nutritional supplements (ONS), while the control group was treated with diet combined with dietary nutrition education. The EORTC(European Organization for Research on Treatment of Cancer)cancer patients' quality-of-life scale (QLQ-C30) was used to evaluate the quality of life of these patients before chemotherapy and after 7 to 14 days of chemotherapy.Results Scores of general health, physical function, role function, emotional function, cognitive function, social function and fatigue were significantly different between the two groups (t=0.006, 0.012, 0.040, 0.039, 0.028, 0.017, 0.006;P＜0.05). The proportion of reduced chemotherapy, delayed chemotherapy and discontinuation of chemotherapy in the observation group was significantly lower than that of the control group(P＜0.05).Conclusions Diet combined with oral nutrition can improve the quality of life of patients with recurrent or metastatic gastric cancer and with PG-SGA scores of 2 to 3 more significantly than diet combined with diet nutrition education, leading to less fatigue, better physical function and higher compliance with chemotherapy.

Key words： gastric cancer chemotherapy nutritional intervention quality-of-life

Received: 20 January 2018

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	Articles by authors
	ZHOU Qi
	CUI Jianxiong
	LIN Wuhua
	HUANG Qiantang
	and JIANG Junying

Cite this article:

ZHOU Qi,CUI Jianxiong,LIN Wuhua等. Effect of nutrition intervention on quality of life and chemotherapy compliance of patients with recurrence or metastasis of gastric cancer[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(5): 507-510.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2018/V29/I5/507

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