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Meta-analysis of transrectal and transperineal prostate biopsy for diagnosis of prostate cancer |
WANG Tao, WANG Qunsuo, WANG Songtao |
The First Department of Surgery, Beijing Municipal Crops Hospital of Chinese People’s Armed Police Force, Beijing 100027, China |
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Abstract Objective To assess the efficacy of transrectal (TR) vs transperineal (TP) prostate biopsy in the diagnosis of prostate cancer.Methods Such databases as PubMed,Embase, Web of Science, CNKI and Baidu Scholar were searched systematically. The meta-analysis was conducted using the Review manager 5.3 software. The odds ratio of the combined 95% confidence interval was calculated to assess the difference in detection rates of prostate cancer between the rectal (TR) and perineal (TP) groups. A total of 1561 patients were enrolled and randomized to the rectal (TR) and perineal (TP) groups.Results Finally, five studies were included in the meta-analysis. The results showed that no significant difference was found in the detection rate of prostate cancer (OR=1.09, 95% CI 0.95-1.25) or PSA levels (OR=-0.13, 95% CI -0.71-0.45). However, in terms of the prostate volume, there was significant difference between the two groups(OR=-3.28, 95% CI -6.40--0.6).Conclusions There is no statistically significant difference in the PCA detection rate between TP prostate biopsy and TR prostate biopsy.
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Received: 05 November 2018
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