Predictive value of TIMI risk scores for long-term prognosis in patients with acute myocardial infarction
XI Ke1, LIU Hui1, WANG Li2
1.Department of Headquarters,the Third Medical Center,Chinese PLA General Hospital, Beijing 100089, China; 2. Department of Medical,Beijing Public Security Hospital, Beijing 100121, China
AbstractObjective To investigate the predictive value of TIMI risk scores for thrombolytic therapy of myocardial infarction in patients with acute myocardial infarction.Methods The present data was obtained from a retrospective analysis. A total of 2958 cases of acute myocardial infarction treated in our hospital between January 1,2014 and December 31,2015 were selected, who completed 3 years of follow-up after discharge. The TIMI risk score was recorded of each patient to follow up on the endpoint events within 3 years.Results The incidence of endpoint events in patients with different risk stratification was compared. The incidence was 99.65% for the high score group, 35.35% for the middle score group, and 13.71% for the low score group, so the difference was statistically significant (P<0.05). The three-year mortality rate of patients with different risk stratification was compared: 19.96% for the high score group, 5.33% for the middle score group and 1.31% for the low score group. The difference was also of statistical significance (P<0.05).The AUC of the TIMI risk score was 0.7996, while 95%CI was 0.7962-0.8030.Conclusions The higher the TIMI risk score in AMI patients, the higher the incidence of endpoint events within 3 years of follow-up, the higher fatality rate and the worse long-term prognosis. TIMI risk scores can effectively help predict the prognosis in patients with AMI.
XI Ke,LIU Hui,WANG Li. Predictive value of TIMI risk scores for long-term prognosis in patients with acute myocardial infarction[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2019, 30(9): 791-793.
Littnerova S, Kala P, Jarkovsky J, et al. GRACE score among six risk scoring systems (CADILLAC, PAMI, TIMI, Dynamic TIMI, Zwolle)demonstrated the best predictive value for prediction of long-term mortality in patients with ST-elevation myocardial infarction[J]. PLoS One, 2015,10(4): e0123215.
[2]
Worner F, Cequier A, Bardaji A, et al. Comments on the ESC guidelines for the management of acute myocardial in-farction in patients presenting with ST-segment elevation[J]. Rev Esp Cardiol (Engl Ed), 2013, 66(1):5-11.
[3]
高晓津,杨进刚,吴 超,等. TIMI 风险评分与 GRACE 风险评分对中国 ST 段抬高型心肌梗死患者院内死亡率的预测价值[J].中国循环杂志,2018,33(6):529-534.
[4]
Thygesen K, Alpert J S, Jaffe A S, et al. Third universal definition of myocardial infarction[J]. Circulation, 2012, 126(16): 2020-2035.
[5]
Morrow D A, Antman E M, Charlesworth A, et al. TIMI risk score for ST-elevation myocardial infarction: a convenient, bedside, clinical score for risk assessment at presentation: an intravenous nPA for treatment of infarcting myocardium early II trial substudy[J]. Circulation, 2000,102(17): 2031-2037.
Amin S T, Morrow D A, Braunwald E, et al. Dynamic TIMI risk score for STEMI[J]. J Am Heart Assoc, 2013, 2(1): e003269.
[11]
De Luca G, Suryapranata H, Van Hof A W, et al. Prognostic assessment of patients with acute myocardial infarction treated with primary angioplasty: implications for early discharge[J]. Circulation, 2004, 109(22): 2737-2743.
[12]
Halkin A, Singh M, Nikolsky E, et al. Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction: the CADILLAC risk score[J]. J Am Coll Cardiol, 2005, 45(9): 1397-1405.
2019, Vol. 30 
