单孔胸腔镜术后罗哌卡因复合右美托咪啶前锯肌平面阻滞联合静脉镇痛效果

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Abstract Objective To observe the effect of ultrasound-guided anterior serratus plane blocking by ropivacaine combined with dexmedetomidine on postoperative analgesia in patients undergoing single-hole thoracoscopic lobectomy.Methods A total of 150 patients undergoing single-hole thoracoscopic lobectomy in our hospital between January 2019 and April 2020 were randomly divided into three groups:group R,group RD,and group C(control group) ,with 50 cases in each.After surgery,patients in group R underwent ultrasound-guided anterior serratus plane blocking with 0.375% ropivacaine 20 ml,patients in group RD with 0.375% ropivacaine and 0.5 μg/kg dexmedetomidine 20ml,and group C with NS 20 ml.The three groups of patients were given intravenous analgesia pumps postoperatively.VAS scores and the number of effective presses at the analgesic pump were calculated before surgery,2 ,6,12,24,and 48 h after surgery.The incidence of adverse reactions such as nausea and vomiting,itching,hypotension,bradycardia and respiratory depression with 48 h of surgery was also recorded.Results VAS scores and effective numbers of presses at the analgesic pump were lower in group R than in group C at 2,6 and 12 h after surgery(P<0.05).VAS scores and effective numbers of presses at the analgesic pump in group RD were lower than in group C at 2,6,12 and 24 h after surgery(P<0.05).VAS scores and effective numbers of presses at the analgesic pump in group RD were lower than in group R at the above time points(P<0.05).The total incidence rate of adverse reactions in the three groups was 14%,16% and 42% respectively,while that of adverse reactions in group RD and group R was significantly lower than that of group C(P<0.05).Conclusions Ropivacaine combined with dexmedetomidine for SAPB can significantly reduce postoperative pain of patients undergoing single-hole thoracoscopic lobectomy,reduce the usage of opioid and incidence rate of postoperative nausea,vomiting and hypotension,which should be made more accessible.

Key words： dexmedetomidine ropivacaine anterior serratus plane blocking single-hole thoracoscopic lobectomy postoperative analgesia

Received: 26 May 2020

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	FU Jiannan
	QI Yanfang
	CHEN YU
	LIU Xiaomei

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FU Jiannan,QI Yanfang,CHEN YU等. Effects of ropivacaine combined with dexmedetomidine on postoperative analgesia in patients undergoing single-hole thoracoscopic lobectomy under ultrasound-guided anterior serratus plane blocking[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2020, 31(11): 983-986.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2020/V31/I11/983

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