肌酸激酶、肌酸激酶同工酶、肌钙蛋白指标在新兵身体状况评估中的意义

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Abstract Objective To explore the significance of creatine kinase, creatine kinase isoenzyme and troponin in physical condition assessment of recruits.Methods A total of 1660 recruits from a unit of the People's Armed Police in 2019 were selected as subjects. CK values were measured 14 days after enlistment. Those whose CK values were above 90% quantile were assigned to the high CK group, while those whose CK values were lower than 10% quantile were assigned to the control group. CK, CK-MB, CTnⅠ, previous amounts of physical activity and clinical symptoms were compared between the two groups 14 days and 90 days after enlistment.Results (1) The median CK of the 1660 soldiers 14 days after enlistment was 321 (201, 592) U/L, and the overall distribution was left-skewed. The 95% medical reference value ranged from 33.59 to 1906.53 U/L. (2) Between 14 to 90 days after enlistment, 38 (22.89%) of the 166 samples in the high CK group showed clinical symptoms, compared with 8 (4.82%) in the control group. The difference between the two groups was statistically significant (χ²=22.71,P＜0.01,OR=5.86,95%CI:2.64-13.01). 16 patients (9.64%) in the high CK group had received training before, compared with 35 (21.08%) in the control group. The difference between the two groups was statistically significant (χ²=8.36,P=0.004,OR=0.40, 95%CI:0.21-0.75). (3) 90 days after enlistment, the values of CK-MB and CTnⅠ in both groups were within the normal range. The high CK group had a lower value of CK, greater changes in CK, a lower value of CK-MB and a higher value of CTnⅠ than in the control group.Conclusions It is recommended that the CK medical reference value range from 33.59 to 1906.53 U/L during physical examination of recruits. An increase of serum CK values can be negligible unless there are obvious clinical symptoms. The amount and duration of training may not lead to the increase of CK-MB or CTnⅠ. Detection of serum CK-MB and CTnⅠ is of no clinical significance in case of other positive indications.

Key words： creatine kinase training injury myocardial injury

Received: 20 December 2020

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	HE Yuhui
	WANG Shuyan
	XU Bo
	LIU Li
	LU Guocheng
	DAI Haipeng
	TAO Jinglong

Cite this article:

HE Yuhui,WANG Shuyan,XU Bo等. Significance of creatine kinase, creatine kinase isoenzyme and troponin in physical condition assessment of recruits[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2021, 32(9): 762-764.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2021/V32/I9/762

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