仅手术治疗卵巢未成熟畸胎瘤的Meta分析

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1079 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To systematically evaluate the safety of the only surgical treatment for patients with ovarian immature teratoma (IT). Methods Pubmed, The Cochrane Library, Web of Science, CNKI, WangFang Data were electronically searched to collect studies on the prognostic outcomes of patients with pure ovarian immature teratoma treated only by surgery and followed up strategy from January 1st, 1990 to February 16th, 2022. Four reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies. Meta-analysis was then performed with STATA software. Results A total of 3 non-randomized cohort studies and 5 case report studies involving 201 patients were included. Most of the patients were in the early stage. twenty-one patients had relapse, and meta-analysis showed that the relapse rate (95%CI) was 5.2%(2.0%,9.4%). In patients with stageⅠ G₂/G₃ pure ovarian IT, the relapse rate (95%CI) was 6.1%(0.3%,16.0%). Three patients died. Conclusions More high-quality studies are needed to determine whether patients with stage Ⅰ G₂/G₃ pure ovarian IT can be treated with surgery alone.

Key words： ovarian immature teratoma surgery follow up relapse pathological grading meta-analysis

Received: 11 July 2022

ZTFLH:

R711.75

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LIU Chuanli
	LIU Jinlong
	CHEN Xiao
	ZHANG Yan
	CHEN Jun
	SUN Yang
	WU Siyu

Cite this article:

LIU Chuanli,LIU Jinlong,CHEN Xiao等. Meta-analysis of only surgical treatment of ovarian immature teratoma[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2023, 34(6): 461-464.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2023/V34/I6/461

[1]	吕炳建, 程亮. 卵巢生殖细胞肿瘤的临床病理学研究进展[J]. 中华病理学杂志, 2015, 44(12):922-925.
[2]	Berney DM, Stoneham S, Arora R, et al. Ovarian germ cell tumour classification: views from the testis[J]. Histopathology, 2020, 76(1):25-36.
[3]	National Comprehensive Cancer Network, Inc. Ovarian cancer including fallopian tube cancer and primary peritoneal cancer(Version 3.2021)[EB/OL].[2021-09-09]. http://www. nccn.org/patients
[4]	曾宪涛, 庄丽萍, 杨宗国, 等. Meta分析系列之七:非随机实验性研究、诊断性试验及动物实验的质量评价工具[J]. 中国循证心血管医学杂志, 2012, 4(6):496-499.
[5]	Wang D, Zhu S, Jia C, et al. Role of staging surgery and adjuvant chemotherapy in adult patients with apparent stage I pure immature ovarian teratoma after fertility-sparing surgery[J]. Int J Gynecol Cancer, 2020, 30(5):664-669.
[6]	Bonazzi C, Peccatori F, Colombo N, et al. Pure ovarian immature teratoma, a unique and curable disease: 10 years' experience of 32 prospectively treated patients[J]. Obstet Gynecol, 1994, 84(4):598-604.
[7]	Bergamini A, Sarwar N, Ferrandina G, et al. Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? an international multicenter analysis[J]. Eur J Cancer, 2020, 137:136-143.
[8]	Vicus D, Beiner M E, Clarke B, et al. Ovarian immature teratoma: treatment and outcome in a single institutional cohort[J]. Gynecol Oncol, 2011, 123(1):50-53.
[9]	Mangili G, Giorda G, Ferrandina G, et al. Surveillance alone in stage I malignant ovarian germ cell tumors: a MITO (Multicenter Italian Trials in Ovarian cancer) prospective observational study[J]. Int J Gynecol Cancer, 2021, 31(9):1242-1247.
[10]	Shinkai T, Masumoto K, Chiba F, et al. Pediatric ovarian immature teratoma: histological grading and clinical characteristics[J]. J Pediatr Surg, 2020, 55(4):707-710.
[11]	Pavone R, Dijoud F, Galmiche L, et al. Pure pediatric ovarian immature teratomas: the french experience[J]. Pediatr Blood Cancer, 2020, 67(4):e28186.
[12]	Alwazzan A B, Popowich S, Dean E, et al. Pure immature teratoma of the ovary in adults: thirty-year experience of a single tertiary care center[J]. Int J Gynecol Cancer, 2015, 25(9):1616-1622.
[13]	Jorge S, Jones N L, Chen L, et al. Characteristics, treatment and outcomes of women with immature ovarian teratoma, 1998-2012[J]. Gynecol Oncol, 2016, 142(2):261-266.
[14]	Pashankar F, Hale J P, Dang H, et al. Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the malignant germ cell tumor international collaborative[J]. Cancer, 2016, 122(2):230-237.
[15]	Cushing B, Giller R, Ablin A, et al. Surgical resection alone is effective treatment for ovarian immature teratoma in children and adolescents: a report of the pediatric oncology group and the children's cancer group[J]. Am J Obstet Gynecol, 1999, 181(2):353-358.
[16]	Heifetz S A, Cushing B, Giller R, et al. Immature teratomas in children: pathologic considerations: a report from the combined pediatric oncology group/children's cancer group[J]. Am J Surg Pathol, 1998, 22(9):1115-1124.
[17]	杨婷, 王珊, 胡显良. 32例小儿未成熟畸胎瘤临床诊疗特点回顾分析[J]. 中国小儿血液与肿瘤杂志, 2015, 20(5):245-250.
[18]	刘伟, 张丽虹, 曲玉清, 等. 卵巢混合性生殖细胞肿瘤病理特征及诊断分析[J]. 中国临床新医学, 2020, 13(10):1031-1035.
[19]	WHO Classification of Tumours Editorial Board. Female genital tumours. Lyon (France): International Agency for Research on Cancer (WHO classification of tumours series, 5th ed.; vol.4)[EB/OL].
	[2020].http://publications.iarc.fr/592