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Effect of prevention and treatment of hyperuricemia in high altitude special service personnel under integrated medical model |
ZHANG Lixiang1, HU Yanan4, ZHANG Weiqiang1, CHEN Lei2, LIU Jie3, WANG Siming5, LI Zhonghua1 |
1. Department of Health Management, 3. Department of Naval Recuperation, 4. Department of Chinese medicine and physiotherapy , Yantai Special Service Recuperation Center of Chinese People’s Armed Police Force, Yantai 264000, China; 2. the 9th Convalesce Department of Beidaihe Rehabilitation and Convalescence Center of PLA Joint Logistic Support Force, Qinhuangdao 066100, China; 5. Department of Endocrinology, the 970th Hospital of PLA Joint Logistic Support Force |
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Abstract Objective To explore the effect of prevention and treatment of hyperuricemia in high altitude special service personnel under integrated medical model. Methods A total of 129 high altitude special service personnel with hyperuricemia admitted to Yantai Special Service Recuperation Center of Chinese People’s Armed Police Force from January 2020 to December 2021 were selected as the study objects, and were randomly divided into the experimental group (86 cases) and control group (43 cases) according to the ratio of 2∶1. The experimental group adopted a multidisciplinary approach under integrated medicine to carry out individualized management of health assessment, health education, health promotion and health monitoring, while the control group received routine health management. The intervention period was 12 months, and the changes of blood uric acid, blood lipid, kidney function, gout attack and other related indexes were compared between the two groups after intervention. Results After 12-month intervention, 8 patients in the experimental group and 11 patients in the control group were lost to follow-up. The implementation rates of the intervention program in the experimental group and the control group were 83.33% (78 cases) and 81.25% (32 cases), respectively. After intervention, the serum uric acid level of both groups significantly decreased (P<0.01), and the serum uric acid level of the experimental group was lower than that of the control group (425.07±14.21μmol/L vs. 474.26±25.56 μmol/L, t=-12.86, P=0.000). After intervention, 18 cases (23.08%) in the experimental group and 6 cases (18.75%) in the control group stopped using urico-lowering drugs completely. After intervention, the number of arthritic turgout, the number of gout attacks (15.38% vs. 34.38%, χ2=4.948), the frequency and severity, and the detection rate of fatty liver(17.95% vs. 56.25%,χ2=14.088), in the experimental group were lower than those in the control group, and the difference was statistically significant (P<0.05). Conclusions The health management model under integrated medicine can significantly reduce the blood uric acid level and the frequency and degree of gout attacks, and significantly improve the level of health knowledge and health behavior.
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Received: 01 January 2024
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