多回波快速自旋回波T2 mapping定量技术评价 心肌T2值的价值

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Abstract Objective To investigate the clinical feasibility and repeatability of a quantitative T₂ mapping technique by multi-echo fast spin-echo (MEFSE), and to evaluate the left ventricular myocardial T₂ values in different segments. Methods With a 3.0T magnetic resonance (MR) imaging system, according to descriptive research method, cardiovascular magnetic imaging(CMR)was performed in 30 healthy volunteers to investigate the clinical feasibility and repeatability of the quantitative MEFSE T₂ mapping technique, combined with Cine and T2WI. T₂ values in 17 segments of myocardium and different blood supply areas were measured and compared using one-way ANOVA. The agreement of two radiologists was evaluated by Bland-Altman method and Pearsosn correlation analysis. Results There were differences in the T₂ values between some of 17 segmental myocardia (P＜0.01). T₂ values were similar in different blood supply areas (F=1.656, P=0.192). Mean myocardial T2 values from the base to the apex were different (F=14.245,P＜0.01): (71.6±7.1) ms (base), (77.3±9.2) ms (middle), (83.0±8.5)ms(apex).According to the Bland—Altman method and Pearson correlation analysis, the measurement of T₂ values had a good inter-observer agreement [95% limits of agreement (-6.1,24.8) ms, correlation coefficient r=0.809]. Conclusions Quantitative CMR MEFSE T₂mapping technology is feasible and repeatable.Myocardial T₂ reference values for the specific CMR setting are provided and they have regional variation.

Key words： cardiac magnetic resonance T₂ mapping normal volunteers

Received: 14 May 2015

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	Articles by authors
	LIU Mingxi
	ZHANG Wanshi
	ZHANG Ziheng
	MENG Limin
	XU Xianrong
	TIAN Jianwei
	GONG Wanfeng
	and LIU Jie

Cite this article:

LIU Mingxi,ZHANG Wanshi,ZHANG Ziheng等. A quantitative T₂ mapping technique by multi-echo fast spin-echo in cardiac magnetic resonance[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2015, 26(10): 1031-1035.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2015/V26/I10/1031

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